Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor.
about
Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemiaFunctional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNADetection of three novel translocation and specific common chromosomal break sites in malignant melanoma by spectral karyotypingCharacterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1Intrachromosomal rearrangements fusing L-myc and rlf in small-cell lung cancerThe PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3Prep2: cloning and expression of a new prep family memberE2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 proteinA fusion protein formed by L-myc and a novel gene in SCLCStructural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complexPbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cellsThe novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativityAnalysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animalsPBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteinsHOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cellsA new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphomaSite-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemiaHOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemiaThe retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork headThe HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genesThe t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcriptFusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemiaThe tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox proteinProtein heterogeneity in the human Ro/SSA ribonucleoproteins. The 52- and 60-kD Ro/SSA autoantigens are encoded by separate genesGeneration of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemiaDNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLFFusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocationDNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion proteinRearrangements of the tal-1 locus as clonal markers for T cell acute lymphoblastic leukemiaThe Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set geneThe hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in cultureAbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteinsMeis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cellsMeis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 micePbx3 deficiency results in central hypoventilationCritical role for a single leucine residue in leukemia induction by E2A-PBX1
P2860
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P1343
Q22010579-8B1F7526-C7F8-42F9-9E0D-ED10ED3D9B0BQ22254126-82F19345-54E6-4ADD-B7AC-49BF3664E806Q23916994-D61D4493-24E1-40A1-9F7B-13EFC7D931BBQ24293686-C222B2BD-244B-45E5-AE63-48474151F6A0Q24296470-FF58334E-849F-4756-B081-C820CAA3CA8EQ24305387-771D3D15-69C1-410C-B4AC-D6B2412F1D2FQ24313754-E32D726D-17A4-4A1A-95B4-20E98D38153CQ24315315-5F5CA8CF-F805-4E9B-A379-4B3008FF447DQ24316427-2B7FF960-E1EB-4163-8010-86270112E7E2Q24317183-9F3936E5-2639-4DB1-AB6F-127F5C9E955AQ24317529-10811F2E-3BDF-4FE1-B2CE-FA6732AEC451Q24317653-D573C8B2-4A23-4BDF-BE30-18495014BE44Q24533177-FA08ED32-AA28-4E35-A0CE-9CE1A7D59F5FQ24545590-11CBDF0F-2478-42EB-8306-6A44B87C122DQ24554397-8D06F4AF-2797-4513-8835-E3BB4A91A718Q24554512-FF1D0047-0647-4741-AC9A-C75CF503B9DCQ24555667-CA7E0A78-D5F9-48D5-A4F5-B02A7434F983Q24556540-6A15A51D-B091-477C-B2F1-C324945FE8C0Q24561477-2B682101-E77B-4351-9C8A-D326CE7EFDE5Q24562394-D5C89C65-1FB1-44C2-AA71-D33723792E79Q24562963-0AFD9B73-263E-4410-B400-9546D08F722AQ24562984-00EC3311-E491-4710-87C9-F7A7D97693E6Q24564573-3AD1CE5C-3BA4-47E0-86FC-2F5D894B7CC3Q24564693-7E179764-8099-491A-B8B5-23B254EAEE81Q24564741-64043043-D359-4E39-910E-843E0B1B572EQ24594978-04748747-1980-476C-96C6-324EE60D3E21Q24596770-30D6834F-B442-482D-8502-D2E85DB4DEEAQ24609997-2817BADB-21FC-4E78-AE1A-2368EB2F472BQ24612257-0C96E913-9A12-4A4E-9994-31E28D75E02DQ24612650-B2EAA319-9DE2-4808-85E8-230DE5EEF688Q24617887-375C682F-3277-47E3-BE51-A09F50145C3CQ24629399-E3C8EF52-11C6-4063-B19F-08DA0F66BE2FQ24629998-388B4ED8-08A7-4291-AB67-49E4DBE80410Q24632107-008D01D5-DF60-45DC-81A9-2F02FF34EADCQ24644374-2A789379-689B-4381-87BF-76D398EE1430Q24646482-AD88C778-4627-450C-996B-DE1A57F6F22FQ24649670-ACD40002-DDAE-491F-8CFB-30F38AE165CBQ24651171-2B7C135F-FBF6-40A4-A280-1536189278E8Q24670007-9281C93A-2D4F-4D2E-A7E3-18536F9EEF8FQ24670517-E018ED78-3D78-4438-91C5-4F3E52FAD683
P2860
Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor.
description
1990 nî lūn-bûn
@nan
1990 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Chromosomal translocation t(1; ...... chimeric transcription factor.
@ast
Chromosomal translocation t(1; ...... chimeric transcription factor.
@en
type
label
Chromosomal translocation t(1; ...... chimeric transcription factor.
@ast
Chromosomal translocation t(1; ...... chimeric transcription factor.
@en
prefLabel
Chromosomal translocation t(1; ...... chimeric transcription factor.
@ast
Chromosomal translocation t(1; ...... chimeric transcription factor.
@en
P2093
P4510
P1433
P1476
Chromosomal translocation t(1; ...... chimeric transcription factor.
@en
P2093
Mellentin JD
Stanbridge E
Wilkinson J
P304
P356
10.1016/0092-8674(90)90657-Z
P407
P577
1990-02-01T00:00:00Z