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Evidence of premature immune aging in patients thymectomized during early childhood

Evidence of premature immune aging in patients thymectomized during early childhood

http://www.wikidata.org/entity/Q35004387

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The effect of age on thymic function Oral supplementation with Lactobacillus delbrueckii subsp. bulgaricus 8481 enhances systemic immunity in elderly subjects Is immunosenescence influenced by our lifetime "dose" of exercise?Mechanisms shaping the naïve T cell repertoire in the elderly - thymic involution or peripheral homeostatic proliferation?Partners in Crime: The Role of CMV in Immune Dysregulation and Clinical Outcome During HIV Infection Mechanistic insights on immunosenescence and chronic immune activation in HIV-tuberculosis co-infection Aging and immune function: molecular mechanisms to interventions Naïve and memory CD8 T cell pool homeostasis in advanced aging: impact of age and of antigen-specific responses to cytomegalovirus Trends in mortality from septicaemia and pneumonia with economic development: an age-period-cohort analysis Cytomegalovirus infection enhances the immune response to influenza.Thymic fatness and approaches to enhance thymopoietic fitness in aging.Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease.Brief report: deficient thymic output in rheumatoid arthritis despite abundance of prethymic progenitors Autoimmunity and allergy control in adults submitted to complete thymectomy early in infancy.Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution.Evidence for a stepwise program of extrathymic T cell development within the human tonsil Understanding immunosenescence to improve responses to vaccines Evaluating cellular polyfunctionality with a novel polyfunctionality index.Immune senescence: relative contributions of age and cytomegalovirus infection Heterogeneity in thymic emigrants: implications for thymectomy and immunosenescence Restoration of CMV-specific-CD4 T cells with ART occurs early and is greater in those with more advanced immunodeficiency.Polyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults.Immune dysregulation after cardiothoracic surgery and incidental thymectomy: maintenance of regulatory T cells despite impaired thymopoiesis.Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques.NKG2D expression in CD4+ T lymphocytes as a marker of senescence in the aged immune system.Report from the second cytomegalovirus and immunosenescence workshop.The aging immune system and its relationship with cancer Naive T cell maintenance and function in human aging.Associations between virologic and immunologic dynamics in blood and in the male genital tract.A lifespan approach to neuroinflammatory and cognitive disorders: a critical role for glia.CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire Immune aging and challenges for immune protection of the graying population.Mechanisms of immunosenescence: lessons from models of accelerated immune aging.Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age.Impact of Persistent Cytomegalovirus Infection on Dynamic Changes in Human Immune System Profile.Thymus Size and Age-related Thymic Involution: Early Programming, Sexual Dimorphism, Progenitors and Stroma.Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity Age-related changes in CD8 T cell homeostasis and immunity to infection Bim dictates naive CD4 T cell lifespan and the development of age-associated functional defects Efforts of the human immune system to maintain the peripheral CD8+ T cell compartment after childhood thymectomy

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P2860

Evidence of premature immune aging in patients thymectomized during early childhood

http://www.wikidata.org/entity/Q35004387

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

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2009年论文

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name

Evidence of premature immune aging in patients thymectomized during early childhood

@ast

Evidence of premature immune aging in patients thymectomized during early childhood

@en

type

label

Evidence of premature immune aging in patients thymectomized during early childhood

@ast

Evidence of premature immune aging in patients thymectomized during early childhood

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prefLabel

Evidence of premature immune aging in patients thymectomized during early childhood

@ast

Evidence of premature immune aging in patients thymectomized during early childhood

@en

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Journal of Clinical Investigation

P1476

Evidence of premature immune aging in patients thymectomized during early childhood

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P2093

Anne Duperrier

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Christophe Ferrand

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Daniel Sidi

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Delphine Sauce

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Martin Larsen

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Michael Keller

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Solène Fastenackels

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Victor Appay

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P2860

Evidence for extrathymic T cell maturation after thymectomy in infancy

The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in life

Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

The influence of age on T cell generation and TCR diversity

Phenotypic analysis of antigen-specific T lymphocytes

The incidence of congenital heart disease

T-cell quality in memory and protection: implications for vaccine design

Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungs

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo.

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3070-3078

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10.1172/JCI39269

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10

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119

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Beatrix Grubeck-Loebenstein

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2009-09-21T00:00:00Z

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26827881

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19770514

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2752077

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