Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters.
about
Retinol Dehydrogenases Regulate Vitamin A Metabolism for Visual FunctionRPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerizationRetinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissuesRetinoids for treatment of retinal diseasesEndogenous fluorophores enable two-photon imaging of the primate eye.Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice.Retinal degeneration in animal models with a defective visual cycle.An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brainKey enzymes of the retinoid (visual) cycle in vertebrate retinaImprovement in rod and cone function in mouse model of Fundus albipunctatus after pharmacologic treatment with 9-cis-retinal.Molecular pharmacodynamics of emixustat in protection against retinal degeneration.Visualization of retinoid storage and trafficking by two-photon microscopy.Aromatic residues in the substrate cleft of RPE65 protein govern retinol isomerization and modulate its progression.Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice.A microparticle/hydrogel combination drug-delivery system for sustained release of retinoids.Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agentsA novel cone visual cycle in the cone-dominated retina.Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice.Vitamin A derivatives as treatment options for retinal degenerative diseases.Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearanceRPE65 and the Accumulation of Retinyl Esters in Mouse Retinal Pigment Epithelium.
P2860
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P2860
Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters.
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Aberrant metabolites in mouse ...... and storage of retinyl esters.
@ast
Aberrant metabolites in mouse ...... and storage of retinyl esters.
@en
type
label
Aberrant metabolites in mouse ...... and storage of retinyl esters.
@ast
Aberrant metabolites in mouse ...... and storage of retinyl esters.
@en
prefLabel
Aberrant metabolites in mouse ...... and storage of retinyl esters.
@ast
Aberrant metabolites in mouse ...... and storage of retinyl esters.
@en
P2093
P2860
P356
P1433
P1476
Aberrant metabolites in mouse ...... and storage of retinyl esters
@en
P2093
Akiko Maeda
Krzysztof Palczewski
Marcin Golczak
Tadao Maeda
P2860
P304
P356
10.1021/BI052382X
P407
P577
2006-04-01T00:00:00Z