Epitope dominance, competition and T cell affinity maturation.
about
Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccinationIndoctrinating T cells to attack pathogens through homeschoolingStructural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptorDifferent Vaccine Vectors Delivering the Same Antigen Elicit CD8+ T Cell Responses with Distinct Clonotype and Epitope SpecificityTerminal deoxynucleotidyl transferase establishes and broadens antiviral CD8+ T cell immunodominance hierarchiesFel d 4, a cat lipocalin allergenDirect ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutininBiomarkers of safety and immune protection for genetically modified live attenuated leishmania vaccines against visceral leishmaniasis - discovery and implications.Defective B-cell response to T-dependent immunization in lupus-prone miceMemory-like CD8+ T cells generated during homeostatic proliferation defer to antigen-experienced memory cells.Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE.Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes.Baculovirus capsid display potentiates OVA cytotoxic and innate immune responses.Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy.Responses against a subdominant CD8+ T cell epitope protect against immunopathology caused by a dominant epitope.TCR recognition of peptide/MHC class II complexes and superantigensAntigen-specific inhibition of high-avidity T cell target lysis by low-avidity T cells via trogocytosis.A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequenciesBalancing speed and accuracy of polyclonal T cell activation: a role for extracellular feedback.Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogenMagnetovaccination as a novel method to assess and quantify dendritic cell tumor antigen capture and delivery to lymph nodes.Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources.A panel of artificial APCs expressing prevalent HLA alleles permits generation of cytotoxic T cells specific for both dominant and subdominant viral epitopes for adoptive therapy.CD8 T cell competition for dendritic cells in vivo is an early event in activation.A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific mannerCD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity.Altered differentiation, diminished pathogenicity, and regulatory activity of myelin-specific T cells expressing an enhanced affinity TCR.The concept of space and competition in immune regulation.Sculpting the immunological response to dengue fever by polytopic vaccinationUnderstanding the failure of CD8+ T-cell vaccination against simian/human immunodeficiency virus.Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infectionEpitope Prediction Assays Combined with Validation Assays Strongly Narrows down Putative Cytotoxic T Lymphocyte EpitopesNaive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominanceGeneration, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection.Relative dominance of epitope-specific CD8+ T cell responses in an F1 hybrid mouse model of respiratory syncytial virus infection.Unusual features of self-peptide/MHC binding by autoimmune T cell receptorsThe relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes.HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-livesT cells compete by cleaving cell surface CD27 and blocking access to CD70-bearing APCs.Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming
P2860
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P2860
Epitope dominance, competition and T cell affinity maturation.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Epitope dominance, competition and T cell affinity maturation.
@ast
Epitope dominance, competition and T cell affinity maturation.
@en
type
label
Epitope dominance, competition and T cell affinity maturation.
@ast
Epitope dominance, competition and T cell affinity maturation.
@en
prefLabel
Epitope dominance, competition and T cell affinity maturation.
@ast
Epitope dominance, competition and T cell affinity maturation.
@en
P1476
Epitope dominance, competition and T cell affinity maturation.
@en
P2093
Ross M Kedl
P304
P356
10.1016/S0952-7915(02)00009-2
P577
2003-02-01T00:00:00Z