Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor. - Wikidata - wikimedia - TriplyDB

Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.

Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.

http://www.wikidata.org/entity/Q35036482

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Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors Clinicopathological significance of c-KIT mutation in gastrointestinal stromal tumors: a systematic review and meta-analysis Gastrointestinal stromal tumor.Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor Gastrointestinal stromal tumor and its targeted therapeutics.Biomarker Development for the Clinical Activity of the mTOR Inhibitor Everolimus (RAD001): Processes, Limitations, and Further Proposals Targeted therapy for cancer: the gastrointestinal stromal tumor model.Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors.Animal models of soft-tissue sarcoma.Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET.Gastrointestinal stromal tumor - an evolving concept.MTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors.Therapeutic Efficacy Assessment of CK6, a Monoclonal KIT Antibody, in a Panel of Gastrointestinal Stromal Tumor Xenograft Models.Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.Beyond standard therapy: drugs under investigation for the treatment of gastrointestinal stromal tumor.Pathology of gastrointestinal stromal tumors.New developments in mammalian target of rapamycin inhibitors for the treatment of sarcoma Imatinib resistance and microcytic erythrocytosis in a KitV558Δ;T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor.Primordial germ cells and gastrointestinal stromal tumors respond distinctly to a cKit overactivating allele Diagnostic criteria, specific mutations, and genetic predisposition in gastrointestinal stromal tumors.Update on imatinib for gastrointestinal stromal tumors: duration of treatment.Gastrointestinal stromal tumors: management of metastatic disease and emerging therapies.Multidisciplinary treatment of gastrointestinal stromal tumors.Advances in preclinical therapeutics development using small animal imaging and molecular analyses: the gastrointestinal stromal tumors model Kit K641E oncogene up-regulates Sprouty homolog 4 and trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours Optimizing imatinib mesylate treatment in gastrointestinal stromal tumors Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.The GIST paradigm: lessons for other kinase-driven cancers.New molecular targets beyond KIT and PDGFRA in gastrointestinal stromal tumors: present and future.Diagnosis of gastrointestinal stromal tumors from minute specimens: cytomorphology, immunohistochemistry, and molecular diagnostic findings.Ridaforolimus in advanced or metastatic soft tissue and bone sarcomas.Gastrointestinal stromal tumors: what do we know now?MicroRNAs and Gastrointestinal Stromal Tumor.Changes in the structure and function of ICC networks in ICC hyperplasia and gastrointestinal stromal tumors.Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth.CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers.Differential expression of metallothionein in gastrointestinal stromal tumors and gastric carcinomas.Protein kinase C-theta regulates KIT expression and proliferation in gastrointestinal stromal tumors.Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors.Why tyrosine kinase inhibitor resistance is common in advanced gastrointestinal stromal tumors.

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P2860

Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.

http://www.wikidata.org/entity/Q35036482

description

2006 nî lūn-bûn

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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年学术文章

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2006年學術文章

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name

Oncogenic Kit signaling and th ...... astrointestinal stromal tumor.

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Oncogenic Kit signaling and th ...... astrointestinal stromal tumor.

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P2093

Agnes Viale

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Cristina R Antonescu

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Ferdinand Rossi

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Gunhild Sommer

http://www.w3.org/2001/XMLSchema#string

Imke Ehlers

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Katia Manova

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Nicholas D Socci

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

The retinoblastoma protein and cell cycle control

CDK inhibitors: positive and negative regulators of G1-phase progression

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation

Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump.

To cycle or not to cycle: a critical decision in cancer.

Activation of STAT proteins and growth control.

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