Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice. - Wikidata - wikimedia - TriplyDB

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.

http://www.wikidata.org/entity/Q35039989

about

Miz1 deficiency in the mammary gland causes a lactation defect by attenuated Stat5 expression and phosphorylation NOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?Notch1 regulates the functional contribution of RhoC to cervical carcinoma progression Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland.Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion Magnetic nanoparticles coated with polyarabic acid demonstrate enhanced drug delivery and imaging properties for cancer theranostic applications NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitro Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway.Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis.Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies Expression of Β-catenin and c-myc during human common bile duct development: a possible role in the morphogenesis of the common bile duct.Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation.Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia MYC in breast tumor progression NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia.MYC and Breast Cancer.DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation.MYC-xing it up with PIK3CA mutation and resistance to PI3K inhibitors: summit of two giants in breast cancers Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/beta-catenin pathway activation The MEK/ERK pathway promotes NOTCH signalling in pancreatic cancer cells.Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells.HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(-/low) tumor-initiating subpopulation in basal-like breast cancer.A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B- and T-cell malignancies Notch Signaling in T-Cell Development and T-ALL Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.Notch signaling as an important mediator of cardiac repair and regeneration after myocardial infarction.Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth.The double-edged sword of Notch signaling in cancer.Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.

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P2860

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.

http://www.wikidata.org/entity/Q35039989

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006年の論文

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2006年論文

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Myc is a Notch1 transcriptiona ...... mammary tumorigenesis in mice.

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Myc is a Notch1 transcriptiona ...... mammary tumorigenesis in mice.

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Myc is a Notch1 transcriptiona ...... mammary tumorigenesis in mice.

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Myc is a Notch1 transcriptiona ...... mammary tumorigenesis in mice.

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Myc is a Notch1 transcriptiona ...... mammary tumorigenesis in mice.

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Myc is a Notch1 transcriptiona ...... mammary tumorigenesis in mice.

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Myc is a Notch1 transcriptiona ...... mammary tumorigenesis in mice.

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P2093

Apostolos Klinakis

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Hippokratis Kiaris

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Matthias Szabolcs

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P2860

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

Notch signaling: cell fate control and signal integration in development

Involvement of Notch1 in the development of mouse mammary tumors

Analysis of C-MYC function in normal cells via conditional gene-targeted mutation

HES and HERP families: multiple effectors of the Notch signaling pathway

Notch signaling: control of cell communication and cell fate

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo.

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Spyros Artavanis-Tsakonas

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