Involvement of Notch1 in the development of mouse mammary tumors
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The notch ligand JAGGED1 as a target for anti-tumor therapyRole of Notch signaling in cell-fate determination of human mammary stem/progenitor cellsNotch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cellsIs there a role for Notch signalling in human breast cancer?Targeting the Notch signaling pathway in cancer therapeuticsNotch signaling in prostate cancer: a moving targetNOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell DeathCharacterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line.The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiationTargeting specific regions of the Notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer.Notch is a critical regulator in cervical cancer by regulating Numb splicing.Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasionMammary development and breast cancer: the role of stem cellsNOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitroTwo distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic miceDistinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodiesInduction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic).Visfatin promotes cell and tumor growth by upregulating Notch1 in breast cancerMouse mammary tumor virus molecular biology and oncogenesisMammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain.Role of Notch and its oncogenic signaling crosstalk in breast cancer.Common integration sites for MMTV in viral induced mouse mammary tumors.Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumorsModulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epitheliumNOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells.Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity.Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence.Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approachesShared signaling pathways in normal and breast cancer stem cells.Acceleration of mouse mammary tumor virus-induced murine mammary tumorigenesis by a p53 172H transgene: influence of FVB background on tumor latency and identification of novel sites of proviral insertion.Dual regulation of notch1 signaling pathway by adaptor protein fe65Gamma secretase inhibitor enhances sensitivity to doxorubicin in MDA-MB-231 cells.Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy.Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells.Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitorsPotential Therapeutic Role of Z-Isochaihulactone in Lung Cancer through Induction of Apoptosis via Notch Signaling.
P2860
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P2860
Involvement of Notch1 in the development of mouse mammary tumors
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Involvement of Notch1 in the development of mouse mammary tumors
@ast
Involvement of Notch1 in the development of mouse mammary tumors
@en
Involvement of Notch1 in the development of mouse mammary tumors
@nl
type
label
Involvement of Notch1 in the development of mouse mammary tumors
@ast
Involvement of Notch1 in the development of mouse mammary tumors
@en
Involvement of Notch1 in the development of mouse mammary tumors
@nl
prefLabel
Involvement of Notch1 in the development of mouse mammary tumors
@ast
Involvement of Notch1 in the development of mouse mammary tumors
@en
Involvement of Notch1 in the development of mouse mammary tumors
@nl
P2093
P2860
P3181
P356
P1433
P1476
Involvement of Notch1 in the development of mouse mammary tumors
@en
P2093
N Beaulieu
P Jolicoeur
P2860
P2888
P304
P3181
P356
10.1038/SJ.ONC.1202991
P407
P577
1999-10-28T00:00:00Z
P5875
P6179
1053576725