Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
about
Notch regulation of bone development and remodeling and related skeletal disordersPhysiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1Truncating mutations in the last exon of NOTCH3 cause lateral meningocele syndromeOsteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.MiR-199b-5p inhibits osteogenic differentiation in ligamentum flavum cells by targeting JAG1 and modulating the Notch signalling pathway.RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance.Chondrocyte-specific pathology during skeletal growth and therapeutics in a murine model of pseudoachondroplasiaNotch activation as a driver of osteogenic sarcoma.NOTCH-Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine.Transient gamma-secretase inhibition accelerates and enhances fracture repair likely via Notch signaling modulationTNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J.Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone developmentNotch signaling in skeletal health and disease.Canonical Notch activation in osteocytes causes osteopetrosis.Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9.Development of the endochondral skeletonNotch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenanceNOTCH signaling in skeletal progenitors is critical for fracture repair.Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphataseAnabolic actions of Notch on mature bone.Notch Signaling and the Skeleton.Systemic inhibition of canonical Notch signaling results in sustained callus inflammation and alters multiple phases of fracture healing.Hairy and Enhancer of Split-related with YRPW motif (HEY)2 regulates bone remodeling in miceNotch signaling in skeletal stem cells.Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitectureNotch signaling and bone remodeling.Notch signaling pathway promotes osteogenic differentiation of mesenchymal stem cells by enhancing BMP9/Smad signaling.Molecular genetics of osteosarcoma.Notch signaling components are upregulated during both endochondral and intramembranous bone regeneration.Loss of Notch3 Signaling Enhances Osteogenesis of Mesenchymal Stem Cells from Mandibular Torus.TNF and Bone Remodeling.Jagged1 immobilization to an osteoconductive polymer activates the Notch signaling pathway and induces osteogenesis.Hairy and Enhancer of Split-Related With YRPW Motif-Like (HeyL) Is Dispensable for Bone Remodeling in Mice.Notch signaling pathways in human thoracic ossification of the ligamentum flavum.The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.
P2860
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P2860
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
@ast
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
@en
type
label
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
@ast
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
@en
prefLabel
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
@ast
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
@en
P2093
P2860
P356
P1476
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent
@en
P2093
Brendan Lee
Brian Dawson
Elda Munivez
Terry Bertin
P2860
P304
P356
10.1002/JBMR.115
P50
P577
2010-10-01T00:00:00Z