Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses. - Wikidata - wikimedia - TriplyDB

Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses.

Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses.

http://www.wikidata.org/entity/Q35080090

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Clinical development of gene therapy: results and lessons from recent successes Development of Auto Antigen-specific Regulatory T Cells for Diabetes Immunotherapy Restoring immune tolerance in neuromyelitis optica: Part II Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells Oral delivery of Acid Alpha Glucosidase epitopes expressed in plant chloroplasts suppresses antibody formation in treatment of Pompe mice.FVIII-specific human chimeric antigen receptor T-regulatory cells suppress T- and B-cell responses to FVIII.TGF-β in tolerance, development and regulation of immunity Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity.Avidity of human T cell receptor engineered CD4(+) T cells drives T-helper differentiation fate Achievements, challenges and unmet needs for haemophilia patients with inhibitors: Report from a symposium in Paris, France on 20 November 2014.Stem Cell-Derived Regulatory T Cells for Therapeutic Use in Arthritis.Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity.In vivo induction of regulatory T cells for immune tolerance in hemophilia.Engineering less immunogenic and antigenic FVIII proteins.Gene therapy for immune tolerance induction in hemophilia with inhibitors.How antigen specificity directs regulatory T-cell function: self, foreign and engineered specificity.Innovating immune tolerance induction for haemophilia.Life in the shadow of a dominant partner: the FVIII-VWF association and its clinical implications for hemophilia A.Factor VIII inhibitors: Advances in basic and translational science.Complexity of immune responses to AAV transgene products - Example of factor IX.Hemophilia A inhibitor treatment: the promise of engineered T-cell therapy.Circulating FVIII-specific IgG, IgA and IgM memory B cells from haemophilia A patients.Human Tregs Made Antigen Specific by Gene Modification: The Power to Treat Autoimmunity and Antidrug Antibodies with Precision T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated.Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A mice.Engineering Specificity and Function of Therapeutic Regulatory T Cells.From IgG Fusion Proteins to Engineered-Specific Human Regulatory T Cells: A Life of Tolerance.Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A.Engineered Tolerance: Tailoring Development, Function, and Antigen-Specificity of Regulatory T Cells.Regulatory T Cells: Molecular and Cellular Basis for Immunoregulation.Dexamethasone promotes durable factor VIII -specific tolerance in hemophilia A mice via thymic mechanisms.Engineering therapeutic T cells to suppress alloimmune responses using TCRs, CARs, or BARs.Clinical Grade Regulatory CD4+ T Cells (Tregs): Moving Toward Cellular-Based Immunomodulatory Therapies.Gene Therapy With Regulatory T Cells: A Beneficial Alliance.New Perspectives in Rheumatology: May You Live in Interesting Times: Challenges and Opportunities in Lupus Research.Engineered FVIII-expressing cytotoxic T cells target and kill FVIII-specific B cells in vitro and in vivo Chimeric Antigen Receptor (CAR) Treg: A Promising Approach to Inducing Immunological Tolerance

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P2860

Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses.

http://www.wikidata.org/entity/Q35080090

description

2014 nî lūn-bûn

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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Engineered antigen-specific hu ...... cific T- and B-cell responses.

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Engineered antigen-specific hu ...... cific T- and B-cell responses.

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Ai-Hong Zhang

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David W Scott

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Ethan M Shevach

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Kathleen P Pratt

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Robert J Rossi

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Ruth A Ettinger

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Sadiye Amcaoglu Rieder

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Yan Su

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Yong Chan Kim

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P2860

The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia

Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus

Induction of colonic regulatory T cells by indigenous Clostridium species

Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.

Epigenetic control of the foxp3 locus in regulatory T cells

Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.

HLA-DR-restricted T-cell responses to factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P.

Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors

Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10

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1107-1115

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scholarly article

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10.1182/BLOOD-2014-04-566786

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7

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125

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2014-12-10T00:00:00Z

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269719049

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25498909

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immunosuppression

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