Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
about
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1Structure and inhibition of human diamine oxidasePentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translationThe history of African trypanosomiasisNovel amidines and analogues as promising agents against intracellular parasites: a systematic reviewComparative analysis of the omics technologies used to study antimonial, amphotericin B, and pentamidine resistance in leishmaniaAdvances in Development of New Treatment for LeishmaniasisA murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytesRegulatory T cells suppress T cell activation at the pathologic site of human visceral leishmaniasisA new in vivo screening paradigm to accelerate antimalarial drug discoveryTransport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma bruceiDrug resistance in leishmaniasisBiological Efficacy and Toxicity of Diamidines in Myotonic Dystrophy Type 1 Models.The diamidine DB75 targets the nucleus of Plasmodium falciparumHighly active anti-Pneumocystis carinii compounds in a library of novel piperazine-linked bisbenzamidines and related compounds.Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners.Searching for new antimalarial therapeutics amongst known drugs.Influence of DNA structure on adjacent site cooperative binding.Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel.Screening of Potential anti-Trypanosoma cruzi Candidates: In Vitro and In Vivo Studies.Developments in diagnosis and treatment of visceral leishmaniasis during the last decade and future prospects.Repositioning antimicrobial agent pentamidine as a disruptor of the lateral interactions of transmembrane domain 5 of EBV latent membrane protein 1.In vitro selection and in vivo efficacy of piperazine- and alkanediamide-linked bisbenzamidines against Pneumocystis pneumonia in mice.Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles.Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones.A CLAG3 mutation in an amphipathic transmembrane domain alters malaria parasite nutrient channels and confers leupeptin resistance.Selective killing of the human malaria parasite Plasmodium falciparum by a benzylthiazolium dye.Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy.Aromatic diamidines as antiparasitic agents.Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.Antiparasitic compounds that target DNA.Two novel nucleobase/pentamidine transporters from Trypanosoma bruceiIncreasing importance of Balamuthia mandrillarisDrug resistance in African trypanosomiasis: the melarsoprol and pentamidine story.Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptakeTrypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.Drug delivery strategies for therapy of visceral leishmaniasis.
P2860
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P2860
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
@ast
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
@en
type
label
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
@ast
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
@en
prefLabel
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
@ast
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
@en
P2093
P1476
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.
@en
P2093
Michael P Barrett
Patrick G Bray
Stephen A Ward
P304
P356
10.1016/S1471-4922(03)00069-2
P577
2003-05-01T00:00:00Z