Amphiregulin as an autocrine growth factor for c-Ha-ras- and c-erbB-2-transformed human mammary epithelial cells.
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Cripto: a novel epidermal growth factor (EGF)-related peptide in mammary gland development and neoplasiaCripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cellsTyrosine phosphorylation regulates the adhesions of ras-transformed breast epitheliaA differential requirement for the COOH-terminal region of the epidermal growth factor (EGF) receptor in amphiregulin and EGF mitogenic signalingPlatelet-derived growth factor requires epidermal growth factor receptor to activate p21-activated kinase family kinasesSelf-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer.ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial aciniInterleukin 1 alpha and tumor necrosis factor alpha stimulate autocrine amphiregulin expression and proliferation of human papillomavirus-immortalized and carcinoma-derived cervical epithelial cells.A role for K-ras in conferring resistance to the MEK inhibitor, CI-1040.Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivoInterleukin-6 and interleukin-6 soluble receptor regulate proliferation of normal, human papillomavirus-immortalized, and carcinoma-derived cervical cells in vitroAlterations of gene expression in the development of early hyperplastic precursors of breast cancer.Differential regulation of cell proliferation and protease secretion by epidermal growth factor and amphiregulin in tumoral versus normal breast epithelial cellsAmphiregulin induces human ovarian cancer cell invasion by down-regulating E-cadherin expression.Evidence for the transforming activity of a truncated Int6 gene, in vitro.Regulation of heparin-binding EGF-like growth factor expression in Ha-ras transformed human mammary epithelial cells.RAS transformation causes sustained activation of epidermal growth factor receptor and elevation of mitogen-activated protein kinase in human mammary epithelial cells.Tumor necrosis factor-alpha promotes human papillomavirus (HPV) E6/E7 RNA expression and cyclin-dependent kinase activity in HPV-immortalized keratinocytes by a ras-dependent pathway.Antisense expression for amphiregulin suppresses tumorigenicity of a transformed human breast epithelial cell line.Transfection with a CRIPTO anti-sense plasmid suppresses endogenous CRIPTO expression and inhibits transformation in a human embryonal carcinoma cell line.Enhanced expression of heregulin in c-erb B-2 and c-Ha-ras transformed mouse and human mammary epithelial cells.The induction of apoptosis in human mammary luminal epithelial cells by expression of activated c-neu and its abrogation by glucocorticoids.COOH-terminal extended recombinant amphiregulin with bioactivity comparable with naturally derived growth factor.Estrogen-independent activation of erbBs signaling and estrogen receptor alpha in the mouse vagina exposed neonatally to diethylstilbestrol.Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor-targeted therapy.Simultaneous blockage of different EGF-like growth factors results in efficient growth inhibition of human colon carcinoma xenografts.Vascular endothelial (VEGF) and epithelial growth factor (EGF) as well as platelet-activating factor (PAF) and receptors are expressed in the early pregnant canine uterus.Expression of amphiregulin and epidermal growth factor receptor in human breast cancer: analysis of autocriny and stromal-epithelial interactions
P2860
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P2860
Amphiregulin as an autocrine growth factor for c-Ha-ras- and c-erbB-2-transformed human mammary epithelial cells.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Amphiregulin as an autocrine g ...... uman mammary epithelial cells.
@ast
Amphiregulin as an autocrine g ...... uman mammary epithelial cells.
@en
type
label
Amphiregulin as an autocrine g ...... uman mammary epithelial cells.
@ast
Amphiregulin as an autocrine g ...... uman mammary epithelial cells.
@en
prefLabel
Amphiregulin as an autocrine g ...... uman mammary epithelial cells.
@ast
Amphiregulin as an autocrine g ...... uman mammary epithelial cells.
@en
P2093
P2860
P356
P1476
Amphiregulin as an autocrine g ...... uman mammary epithelial cells.
@en
P2093
Ciardiello F
Normanno N
P2860
P304
P356
10.1073/PNAS.91.7.2790
P407
P577
1994-03-01T00:00:00Z