Negative selection--clearing out the bad apples from the T-cell repertoire.
about
ZAP-70 restoration in mice by in vivo thymic electroporationIAN family critically regulates survival and development of T lymphocytes.Insights on FoxN1 biological significance and usages of the "nude" mouse in studies of T-lymphopoiesisTranscriptional regulation by AIRE: molecular mechanisms of central toleranceAntigen-specific T cells: analyses of the needles in the haystackIn utero stem cell transplantation and gene therapy: rationale, history, and recent advances toward clinical applicationThymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance InductionPiecing together the humoral and cellular mechanisms of immune thrombocytopeniaOptimization of specificity in a cellular protein interaction network by negative selection.Peripheral blood mononuclear cell secretome for tissue repairCentral tolerance: learning self-control in the thymusStochastic responses may allow genetically diverse cell populations to optimize performance with simpler signaling networksThe timing of TCR alpha expression critically influences T cell development and selectionDeath pathways in T cell homeostasis and their role in autoimmune diabetes.False occurrences of functional motifs in protein sequences highlight evolutionary constraintsComparative analysis of transcriptional profiling of CD3+, CD4+ and CD8+ T cells identifies novel immune response players in T-cell activation.Subacute oral exposure to dibromoacetic acid induced immunotoxicity and apoptosis in the spleen and thymus of the mice.Immunological tolerance and tumor rejection in embryo-aggregated chimeric mice - lessons for tumor immunity.Regulation of T cell development and activation by creatine kinase B.The mannosylated extracellular domain of Her2/neu produced in P. pastoris induces protective antitumor immunity.Roles of the Src tyrosine kinases Lck and Fyn in regulating gammadeltaTCR signal strengthFoxM1, a forkhead transcription factor is a master cell cycle regulator for mouse mature T cells but not double positive thymocytesGene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma.Coupling of the cell cycle and apoptotic machineries in developing T cells.Inducing local T cell apoptosis with anti-Fas-functionalized polymeric coatings fabricated via surface-initiated photopolymerizations.c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development.Fast on-rates allow short dwell time ligands to activate T cells.Fine-tuning T cell receptor signaling to control T cell developmentT cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival.Development of thymically derived natural regulatory T cells.The role of the thymus in tolerance.Revisiting thymic positive selection and the mature T cell repertoire for antigen.Both positive and negative effects on immune responses by expression of a second class II MHC molecule.Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymusNegative selection assay based on stimulation of T cell receptor transgenic thymocytes with peptide-MHC tetramersFirst use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases.Dendritic cells in the thymus contribute to T-regulatory cell induction.Optimal T-cell receptor affinity for inducing autoimmunity.Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis.
P2860
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P2860
Negative selection--clearing out the bad apples from the T-cell repertoire.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Negative selection--clearing out the bad apples from the T-cell repertoire.
@ast
Negative selection--clearing out the bad apples from the T-cell repertoire.
@en
type
label
Negative selection--clearing out the bad apples from the T-cell repertoire.
@ast
Negative selection--clearing out the bad apples from the T-cell repertoire.
@en
prefLabel
Negative selection--clearing out the bad apples from the T-cell repertoire.
@ast
Negative selection--clearing out the bad apples from the T-cell repertoire.
@en
P356
P1476
Negative selection--clearing out the bad apples from the T-cell repertoire.
@en
P2093
P304
P356
10.1038/NRI1085
P577
2003-05-01T00:00:00Z