about
Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivoImplications of telomere-independent activities of telomerase reverse transcriptase in human cancerNucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNAPulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive oxygen species mechanismsConditional telomerase induction causes proliferation of hair follicle stem cellsIrradiation-induced telomerase activity and gastric cancer risk: a case-control analysis in a Chinese Han population.Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells.Expression and biological-clinical significance of hTR, hTERT and CKS2 in washing fluids of patients with bladder cancer.The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.RFPL3 and CBP synergistically upregulate hTERT activity and promote lung cancer growthInduction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.Mechanism of telomerase activation by v-Rel and its contribution to transformation.Centromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas.Genetic analysis of myc and telomerase interactions in vivo.Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells.Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome.Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis.Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.Mechanisms of human papillomavirus-induced oncogenesis.Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeresTargeting the Hedgehog signaling pathway in cancer: beyond Smoothened.Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16 and activation of the DNA damage response pathwayTelomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres.Human cancer cells harbor T-stumps, a distinct class of extremely short telomeres.Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/β-catenin pathway in human cancer.Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcsHeregulin, a new regulator of telomere length in human cellsTelomere length dynamics in normal hematopoiesis and in disease states characterized by increased stem cell turnover.Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activityTelomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancerAssessing cell and organ senescence biomarkersInhibition of telomerase activity by oleanane triterpenoid CDDO-Me in pancreatic cancer cells is ROS-dependent.Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells.hTERT promotes tumor angiogenesis by activating VEGF via interactions with the Sp1 transcription factor.Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice.Involvement of the oncoprotein c-Myc in viral telomerase RNA gene regulation during Marek's disease virus-induced lymphomagenesis.Effect of vector-expressed shRNAs on hTERT expression.Association between hTERT rs2736100 polymorphism and sensitivity to anti-cancer agentsMultiscale in situ analysis of the role of dyskerin in lung cancer cells.Telomerase- and recombination-independent immortalization of budding yeast.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Evolving views of telomerase and cancer.
@ast
Evolving views of telomerase and cancer.
@en
type
label
Evolving views of telomerase and cancer.
@ast
Evolving views of telomerase and cancer.
@en
prefLabel
Evolving views of telomerase and cancer.
@ast
Evolving views of telomerase and cancer.
@en
P1476
Evolving views of telomerase and cancer.
@en
P2093
William C Hahn
P304
P356
10.1016/S0962-8924(03)00085-0
P577
2003-06-01T00:00:00Z