Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation.
about
A rationally-designed chimeric KDM1A/KDM1B histone demethylase tower domain deletion mutant retaining enzymatic activityHistone demethylases in chromatin biology and beyondLSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factorsPolymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural featuresLSD1 Histone Demethylase Assays and InhibitionExtranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex.Coupling between Histone Conformations and DNA Geometry in Nucleosomes on a Microsecond Timescale: Atomistic Insights into Nucleosome FunctionsLysine-Specific Demethylase 1A (KDM1A/LSD1): Product Recognition and Kinetic Analysis of Full-Length Histones.Touch, act and go: landing and operating on nucleosomes.Epigenetic regulation of development and pathogenesis in fungal plant pathogens.Cryo-electron microscopy of chromatin biology.G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzymeDNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.Stepwise assembly of functional C-terminal REST/NRSF transcriptional repressor complexes as a drug target.Chemically Sumoylated Histone H4 Stimulates Intranucleosomal Demethylation by the LSD1-CoREST Complex.KDM1A microenvironment, its oncogenic potential, and therapeutic significance.The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome.Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex.
P2860
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P2860
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation.
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Interplay among nucleosomal DN ...... SD1-mediated H3 demethylation.
@ast
Interplay among nucleosomal DN ...... SD1-mediated H3 demethylation.
@en
type
label
Interplay among nucleosomal DN ...... SD1-mediated H3 demethylation.
@ast
Interplay among nucleosomal DN ...... SD1-mediated H3 demethylation.
@en
prefLabel
Interplay among nucleosomal DN ...... SD1-mediated H3 demethylation.
@ast
Interplay among nucleosomal DN ...... SD1-mediated H3 demethylation.
@en
P2093
P2860
P50
P356
P1476
Interplay among nucleosomal DN ...... SD1-mediated H3 demethylation.
@en
P2093
Alexander Fish
Dominique Durand
Marcello Tortorici
Patrice Vachette
P2860
P304
P356
10.1073/PNAS.1419468112
P407
P50
P577
2015-02-17T00:00:00Z