Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity.
about
Pernicious attrition and inter-RyR2 CICR current control in cardiac muscleAlterations in T-tubule and dyad structure in heart disease: challenges and opportunities for computational analysesRyanodine Receptor Activation Induces Long-Term Plasticity of Spine Calcium DynamicsLife and death of a cardiac calcium sparkHierarchical clustering of ryanodine receptors enables emergence of a calcium clock in sinoatrial node cells.Computational modeling of subcellular transport and signaling.Store-dependent deactivation: cooling the chain-reaction of myocardial calcium signaling.Cardiac alternans and intracellular calcium cycling.Nonlinear and Stochastic Dynamics in the HeartControl of sarcoplasmic reticulum Ca2+ release by stochastic RyR gating within a 3D model of the cardiac dyad and importance of induction decay for CICR terminationThe timing statistics of spontaneous calcium release in cardiac myocytes.Calcium-voltage coupling in the genesis of early and delayed afterdepolarizations in cardiac myocytesMechanical unloading reverses transverse tubule remodelling and normalizes local Ca(2+)-induced Ca(2+)release in a rodent model of heart failureCytosolic Ca²⁺ buffering determines the intra-SR Ca²⁺ concentration at which cardiac Ca²⁺ sparks terminateRefractoriness of sarcoplasmic reticulum Ca2+ release determines Ca2+ alternans in atrial myocytesCalcium alternans in a couplon network model of ventricular myocytes: role of sarcoplasmic reticulum load.Elementary calcium release events from the sarcoplasmic reticulum in the heart.There and back again: Iterating between population-based modeling and experiments reveals surprising regulation of calcium transients in rat cardiac myocytes.Calcium alternans in cardiac myocytes: order from disorder.Isoproterenol increases the fraction of spark-dependent RyR-mediated leak in ventricular myocytes.PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity.Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca(2+) release events in a rodent model of early stage diabetes: The arrhythmogenic substrate.Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia.Mechanism of calsequestrin regulation of single cardiac ryanodine receptor in normal and pathological conditions.Computational approaches to understand cardiac electrophysiology and arrhythmias.A unified theory of calcium alternans in ventricular myocytes.Parameter sensitivity analysis of stochastic models provides insights into cardiac calcium sparks.Stochastic initiation and termination of calcium-mediated triggered activity in cardiac myocytes.Dynamic local changes in sarcoplasmic reticulum calcium: physiological and pathophysiological roles.Decoding myocardial Ca²⁺ signals across multiple spatial scales: a role for sensitivity analysis.Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca2+ (mis)handling.What is a Ca(2+) wave? Is it like an Electrical Wave?Biphasic decay of the Ca transient results from increased sarcoplasmic reticulum Ca leak.Maximal acceleration of Ca2+ release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes.Cardiac myocyte alternans in intact heart: Influence of cell-cell coupling and β-adrenergic stimulation.Persistence of pro-arrhythmic spatio-temporal calcium patterns in atrial myocytes: a computational study of ping waves.Does the Goldilocks Principle apply to calcium release restitution in heart cells?R4496C RyR2 mutation impairs atrial and ventricular contractility.Modelling cardiac calcium sparks in a three-dimensional reconstruction of a calcium release unit.Calcium homeostasis in a local/global whole cell model of permeabilized ventricular myocytes with a Langevin description of stochastic calcium release.
P2860
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P2860
Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Recovery of cardiac calcium re ...... yanodine receptor sensitivity.
@ast
Recovery of cardiac calcium re ...... yanodine receptor sensitivity.
@en
type
label
Recovery of cardiac calcium re ...... yanodine receptor sensitivity.
@ast
Recovery of cardiac calcium re ...... yanodine receptor sensitivity.
@en
prefLabel
Recovery of cardiac calcium re ...... yanodine receptor sensitivity.
@ast
Recovery of cardiac calcium re ...... yanodine receptor sensitivity.
@en
P2093
P2860
P356
P1476
Recovery of cardiac calcium re ...... yanodine receptor sensitivity.
@en
P2093
Eric A Sobie
Hena R Ramay
P2860
P304
P356
10.1093/CVR/CVR143
P577
2011-05-24T00:00:00Z