Molecular genetics of human obesity-associated MC4R mutations.
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Interactions of human melanocortin 4 receptor with nonpeptide and peptide agonistsHow Does the Brain Implement Adaptive Decision Making to Eat?Unraveling the genetics of human obesity.Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo.Cloning and characterization of the 5'-flanking region of the pig AgRP gene.Food demand and meal size in mice with single or combined disruption of melanocortin type 3 and 4 receptors.Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor.Obesity-linked variants of melanocortin-4 receptor are misfolded in the endoplasmic reticulum and can be rescued to the cell surface by a chemical chaperone.Medical sequencing at the extremes of human body mass.Co-occurrence of two partially inactivating polymorphisms of MC3R is associated with pediatric-onset obesityInteraction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult HealthConstitutive cholesterol-dependent endocytosis of melanocortin-4 receptor (MC4R) is essential to maintain receptor responsiveness to α-melanocyte-stimulating hormone (α-MSH).Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor SignalingAllelic variants of the Melanocortin 4 receptor (MC4R) gene in a South African study groupGenetics of type 2 diabetes mellitus and obesity--a review.Polymorphisms in the NPY2R gene show significant associations with BMI that are additive to FTO, MC4R, and NPFFR2 gene effects.Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice.Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling.Weight loss after bariatric surgery in morbidly obese adolescents with MC4R mutationsPharmacogenetics of antipsychotic-induced weight gain: review and clinical implications.An overview of mongenic and syndromic obesities in humans.Pharmacological characterization of 30 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists, synthetic agonists, and the endogenous agouti-related protein antagonist.Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.Expression studies of six human obesity-related genes in seven tissues from divergent pig breeds.Novel variants in the MC4R and LEPR genes among severely obese children from the Iberian population.A hypercaloric pellet-diet cycle induces obesity and co-morbidities in Wistar rats.Melanocortin-4 receptor signaling is not required for short-term weight loss after sleeve gastrectomy in pediatric patients.Obesity Triggers: Sequencing the Genome Versus Sequencing the Environment.The Human Obesity Gene Map: The 2004 UpdateApplications of Systems Genetics and Biology for Obesity Using Pig ModelsHeritability: The family roots of obesity
P2860
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P2860
Molecular genetics of human obesity-associated MC4R mutations.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Molecular genetics of human obesity-associated MC4R mutations.
@ast
Molecular genetics of human obesity-associated MC4R mutations.
@en
type
label
Molecular genetics of human obesity-associated MC4R mutations.
@ast
Molecular genetics of human obesity-associated MC4R mutations.
@en
prefLabel
Molecular genetics of human obesity-associated MC4R mutations.
@ast
Molecular genetics of human obesity-associated MC4R mutations.
@en
P2093
P50
P1476
Molecular genetics of human obesity-associated MC4R mutations.
@en
P2093
Astrid Shapiro
Beatrice Dubern
Catherine L E Stunff
Cecile Lubrano-Berthelier
Cedric Govaerts
Christian Vaisse
Franck Picart
Karine Clement
Martha Cavazos
Sumei Zhang
P356
10.1111/J.1749-6632.2003.TB03161.X
P407
P577
2003-06-01T00:00:00Z