Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage - Wikidata - wikimedia - TriplyDB

Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

http://www.wikidata.org/entity/Q35191895

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Specific interaction between 14-3-3 isoforms and the human CDC25B phosphatase Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression Cdc25B functions as a novel coactivator for the steroid receptors Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function Roles of Chk1 in cell biology and cancer therapy Regulating mammalian checkpoints through Cdc25 inactivation.The Schizosaccharomyces pombe checkpoint kinases Chk1 and Cds1 are important for cell survival in response to cisplatin Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345 The oxidative stress responsive transcription factor Pap1 confers DNA damage resistance on checkpoint-deficient fission yeast cells A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe.Importance of a C-terminal conserved region of Chk1 for checkpoint function.Vpr protein of human immunodeficiency virus type 1 binds to 14-3-3 proteins and facilitates complex formation with Cdc25C: implications for cell cycle arrest Rad18 is required for DNA repair and checkpoint responses in fission yeast.S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells.Redundant mechanisms prevent mitotic entry following replication arrest in the absence of Cdc25 hyper-phosphorylation in fission yeast.Analysis of fission yeast primase defines the checkpoint responses to aberrant S phase initiation.Mechanisms of cell-cycle checkpoints: at the crossroads of carcinogenesis and drug discovery.Yeast 14-3-3 proteins.14-3-3 proteins: key regulators of cell division, signalling and apoptosis.Drosophila wee1 has an essential role in the nuclear divisions of early embryogenesis Antagonism of Chk1 signaling in the G2 DNA damage checkpoint by dominant alleles of Cdr1 DNA damage: a sensible mediator of the differentiation decision in hematopoietic stem cells and in leukemia.The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53.Nuclear factories for signalling and repairing DNA double strand breaks in living fission yeast.Repair of topoisomerase I-mediated DNA damage.Regulation of Chk1 by its C-terminal domain.Cds1 controls the release of Cdc14-like phosphatase Flp1 from the nucleolus to drive full activation of the checkpoint response to replication stress in fission yeast.HMGA2 inhibits apoptosis through interaction with ATR-CHK1 signaling complex in human cancer cells.DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding.The 14-3-3 proteins Rad24 and Rad25 negatively regulate Byr2 by affecting its localization in Schizosaccharomyces pombe.Regulation of Chk1 kinase by autoinhibition and ATR-mediated phosphorylation.Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1.KA1-targeted regulatory domain mutations activate Chk1 in the absence of DNA damage A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response.Cdc25B activity is regulated by 14-3-3.The fission yeast MAPK Spc1 senses perturbations in Cdc25 and Wee1 activities and targets Rad24 to restore this balance.Fission yeast Rnf4 homologs are required for DNA repair.

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P2860

Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

http://www.wikidata.org/entity/Q35191895

description

1999 nî lūn-bûn

@nan

1999 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի մարտին հրատարակված գիտական հոդված

@hy

1999年の論文

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1999年論文

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1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

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Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

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type

label

Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

@ast

Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

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prefLabel

Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

@ast

Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

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Genes & Development

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Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage

@en

P2093

L Chen

http://www.w3.org/2001/XMLSchema#string

N C Walworth

http://www.w3.org/2001/XMLSchema#string

T H Liu

http://www.w3.org/2001/XMLSchema#string

P2860

14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

Activation-modulated association of 14-3-3 proteins with Cbl in T cells

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

14-3-3 proteins associate with cdc25 phosphatases

DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

Crystal structure of the zeta isoform of the 14-3-3 protein

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

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675-685

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scholarly article

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10.1101/GAD.13.6.675

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6

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13

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10090724

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316547

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