Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo - Wikidata - wikimedia - TriplyDB

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

http://www.wikidata.org/entity/Q35207717

about

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence.Suppressor role of activating transcription factor 2 (ATF2) in skin cancer The prolyl isomerase Pin1 in breast development and cancer Signalling in the epidermis: the E2F cell cycle regulatory pathway in epidermal morphogenesis, regeneration and transformation RAS oncogenes: weaving a tumorigenic web Cyclins: roles in mitogenic signaling and oncogenic transformation The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis SPIN90 knockdown attenuates the formation and movement of endosomal vesicles in the early stages of epidermal growth factor receptor endocytosis.A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.ETS-targeted therapy: can it substitute for MEK inhibitors?Insights into cancer from transgenic mouse models.Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis A new functional classification of tumor-suppressing genes and its therapeutic implications.pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway.A novel role for integrin-linked kinase in epithelial sheet morphogenesis The thyroid hormone receptors modulate the skin response to retinoids Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes.Specific protection against breast cancers by cyclin D1 ablation.Paradigms of growth control: relation to Cdk activation.Inhibition of tumor growth and metastasis by non-small cell lung cancer cells transfected with cyclin D1-targeted siRNA The mammalian Jun proteins: redundancy and specificity.Surprising dependency for retinoblastoma protein in ras-mediated tumorigenesis Signaling networks that link cell proliferation and cell fate.Cyclin T1 overexpression induces malignant transformation and tumor growth.Cell cycle dysregulation in oral cancer.A mouse model of human oral-esophageal cancer.The thyroid hormone receptors as modulators of skin proliferation and inflammation Cyclin D1 governs adhesion and motility of macrophages.Alterations in signal transduction pathways implicated in tumour progression during multistage mouse skin carcinogenesis.Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation.Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation.Combined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.Cyclin D2 overexpression in transgenic mice induces thymic and epidermal hyperplasia whereas cyclin D3 expression results only in epidermal hyperplasia.IκB kinase alpha and cancer HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis The requirement for cyclin D function in tumor maintenance.

P2860

Q24535558-86BCB6EB-9A9B-4E65-9905-020E3349F867 Q24540051-9ED7B052-6B19-41E8-B8AB-DD98200B0B6D Q24652406-65FE151D-1B9A-4CDF-A1BD-67616E039D0C Q24795560-04389889-425C-4CA0-AF4C-25EB145024E2 Q24810136-01D07985-D08D-40A6-B3EF-35C27D7B3592 Q28250360-02D9E99D-D1BA-4FC2-93E7-605EA352B6CE Q28289852-B8264FAB-47D0-437C-B46B-A5F6159DB694 Q28588064-1AB90696-26EB-4592-8BC8-3ED1B52AA6D9 Q28594871-88A6D359-49D8-43B5-B6C8-F0509E160185 Q30009512-27F5B154-CC89-44C9-855B-B6D92981215B Q30828170-77F571F0-3BAE-4ACF-AA4F-ADFE0A51B661 Q33638827-98E571D4-133C-4DA3-819D-6B96BA848FF4 Q33643327-74044B2B-1487-4968-9081-C4CF6863E9E5 Q33810358-F3A08DE1-1DAC-4B99-B0CC-598472224F1C Q33843457-9F189915-E04E-4F89-AB72-BD0E03524E9C Q33854336-E5E08AB8-4499-4EAB-B0A9-9F7CEC711A39 Q33872322-D9884AC0-67A1-45B8-8705-13AF9231C6D4 Q33938365-54F545D9-8E37-4B1C-9A26-B99481183FFC Q34000076-1BC2C365-D930-473B-BACB-FAED141809C6 Q34009230-E366F1FD-1DBB-4E31-BA1C-38F1AC16BF78 Q34082446-5DE93CB5-B2CD-4905-A4EC-0F817F437EAA Q34130676-050202D9-5133-40BB-8004-3E8B071A8EFB Q34167898-CDE649AF-F692-4C47-B3F9-4D662A2AE639 Q34279339-649CD0C4-C0F2-43DE-9F59-64CA22F7CBDC Q34353737-EE6C4EB1-48CF-48A4-8377-AE6642A3B5C0 Q34502845-69012DEA-2C23-40CD-9C8F-717DF712732A Q34582060-D434678B-C497-4CB2-BBE7-091625EAB981 Q34720567-E3719708-B089-4A20-8CE2-96E9C3745488 Q34796816-AC339A95-7FE6-4E68-86C0-187149EFEC0C Q35085091-6BDA4DF3-6A50-4691-A1B9-5F84E8A05591 Q35153599-B9F0BC9B-547F-4B62-8C77-662375895AC8 Q35154879-9DB0883D-0DB0-4433-A31A-D33DA516E782 Q35747628-0E3C95F6-19DF-4E84-8E9D-6346886DA0D5 Q35792968-39735A4C-0F52-4C3F-9BC9-BFF1EDB74C19 Q35801403-A7B58FD6-6485-4303-B2DD-195F008E9108 Q35805158-B3858EE3-45CD-4B0D-9F0F-7B1450A58FBC Q35829500-61123421-1415-460E-8DC6-166F73618365 Q35872007-F82EEEF0-BA6E-42DF-8840-92A8C3E5DC32 Q35919080-01B93871-302E-44A7-95CB-32BC23D2E7AC Q36366702-8763D482-387D-47AB-8512-D2AA6357F70F

P2860

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

http://www.wikidata.org/entity/Q35207717

description

1998 nî lūn-bûn

@nan

1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Reduced skin tumor development ...... oncogenic ras pathway in vivo

@ast

Reduced skin tumor development ...... oncogenic ras pathway in vivo

@en

type

label

Reduced skin tumor development ...... oncogenic ras pathway in vivo

@ast

Reduced skin tumor development ...... oncogenic ras pathway in vivo

@en

prefLabel

Reduced skin tumor development ...... oncogenic ras pathway in vivo

@ast

Reduced skin tumor development ...... oncogenic ras pathway in vivo

@en

P1433

Q35207717-2466229C-5101-4DE8-91C0-06AC215D2637

P1476

Q35207717-0CFFB62A-DB53-41C9-9985-07A1FC22F9C2

P2093

Q35207717-035D5887-17F5-41BA-BAEF-4002A89D7318

Q35207717-0D25A268-CEE6-4C2F-A76E-567114A3AE9D

Q35207717-5B7EB201-EFD5-47CC-A66E-6FB7517136F8

Q35207717-6AB3916D-67BC-4FB9-B057-FC6908B700BA

Q35207717-6EFE4158-530D-4EA4-9E52-014403FEFC65

Q35207717-79A915FD-5207-49B6-A137-F09826D9C535

Q35207717-87CF3CC9-96C6-47C8-95AA-CE21101B0ECE

Q35207717-9359F663-5E8E-4218-A724-DE337AADF25C

Q35207717-CA1EDFDE-3148-47EA-AFF3-78A52EF92E14

Q35207717-E64F8255-6DE4-40EC-94E6-994841126168

P2860

Q35207717-14C57FD1-069D-455D-8915-4B3746183FA9

Q35207717-1BC78D7B-9C5F-43A6-A3A8-AD0BA7C60789

Q35207717-22A0CA8A-30BC-4608-9E8E-9D18F66BAE9E

Q35207717-2578E6A5-3671-41FE-B7A8-14CA90AB6DAB

Q35207717-37C2DBA3-2256-484A-83B2-2174077F02C9

Q35207717-38728473-4EC5-47D8-BEAC-D6B83A80C118

Q35207717-3CE5DE6B-92C2-4CBE-8B16-0D2B6C951331

Q35207717-51EE3257-95FA-4D1F-844B-7A2BACDB4CC4

Q35207717-62CE096C-C7AE-45EA-8193-2A7F405A3D7A

Q35207717-6766FD5B-89B1-4032-8214-DBB608C40483

P304

Q35207717-5C492943-F632-47B0-B1E6-D5831A92DDD2

P31

Q35207717-3312FA91-5AB6-4C7D-AD27-A1CD0CB5A710

P356

Q35207717-A741C7E9-3C42-4821-A8FE-6B1FE9E528CD

P433

Q35207717-4A442B0A-216A-4F5B-B3D4-4EFA636DC78B

P478

Q35207717-5E41B4EB-3848-4642-9645-ABA7B2898F59

P577

Q35207717-C8D59585-C5C1-43F0-8A27-396EF263F5B0

P5875

Q35207717-1949EA52-8000-4899-946D-541C68831F58

P698

Q35207717-DDFE71C0-41DE-4770-BBF9-BC5240F55D49

P932

Q35207717-CC4B74FC-DDCD-40E7-87DD-DAF542289B64

P356

P1433

Genes & Development

P1476

Reduced skin tumor development ...... oncogenic ras pathway in vivo

@en

P2093

A B Glick

http://www.w3.org/2001/XMLSchema#string

A I Robles

http://www.w3.org/2001/XMLSchema#string

C J Conti

http://www.w3.org/2001/XMLSchema#string

C Trempus

http://www.w3.org/2001/XMLSchema#string

L Hansen

http://www.w3.org/2001/XMLSchema#string

M L Rodriguez-Puebla

http://www.w3.org/2001/XMLSchema#string

P Sicinski

http://www.w3.org/2001/XMLSchema#string

R A Weinberg

http://www.w3.org/2001/XMLSchema#string

R W Tennant

http://www.w3.org/2001/XMLSchema#string

S H Yuspa

http://www.w3.org/2001/XMLSchema#string

P2860

New functional activities for the p21 family of CDK inhibitors

The retinoblastoma protein and cell cycle control

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

Cancer cell cycles

Inhibitors of mammalian G1 cyclin-dependent kinases

D-type cyclin-dependent kinase activity in mammalian cells

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions.

Follicular origin of epidermal papillomas in v-Ha-ras transgenic TG.AC mouse skin

Cyclin D1 overexpression vs. retinoblastoma inactivation: implications for growth control evasion in non-small cell and small cell lung cancer

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells.

P304

2469-2474

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.12.16.2469

http://www.w3.org/2001/XMLSchema#string

P433

16

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P577

1998-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

13569799

http://www.w3.org/2001/XMLSchema#string

P698

9716400

http://www.w3.org/2001/XMLSchema#string

P932

317082

http://www.w3.org/2001/XMLSchema#string