Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. - Wikidata - wikimedia - TriplyDB

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.

http://www.wikidata.org/entity/Q35207910

about

pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle Restriction beyond the restriction point: mitogen requirement for G2 passage TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes Regulation of TopBP1 oligomerization by Akt/PKB for cell survival Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation.Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4 Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence.PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression Suppression of non-small cell lung tumor development by the let-7 microRNA family E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways Retinoblastoma family genes The retinoblastoma family: twins or distant cousins?Retinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategies Roles and mechanisms of cellular senescence in regulation of tissue homeostasis Molecular mechanisms underlying RB protein function Coordinated regulation of intestinal functions in C. elegans by LIN-35/Rb and SLR-2 Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure.Transcriptional control of stem cell fate by E2Fs and pocket proteins DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway Aberrant regulation of survivin by the RB/E2F family of proteins FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcription Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130 Expression of the lncRNA Maternally Expressed Gene 3 (MEG3) Contributes to the Control of Lung Cancer Cell Proliferation by the Rb Pathway Premature senescence and increased TGFβ signaling in the absence of Tgif1.Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis Repression by RB1 characterizes genes involved in the penultimate stage of erythroid development Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice The cell cycle time of CD8+ T cells responding in vivo is controlled by the type of antigenic stimulus.siRNA-mediated gene silencing: a global genome view.A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.Evidence that stable retroviral transduction and cell survival following DNA integration depend on components of the nonhomologous end joining repair pathway.

P2860

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P2860

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.

http://www.wikidata.org/entity/Q35207910

description

2000 nî lūn-bûn

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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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Targeted disruption of the thr ...... ) control and immortalization.

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Targeted disruption of the thr ...... ) control and immortalization.

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Targeted disruption of the thr ...... ) control and immortalization.

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Targeted disruption of the thr ...... ) control and immortalization.

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Targeted disruption of the thr ...... ) control and immortalization.

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Genes & Development

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Targeted disruption of the thr ...... ) control and immortalization.

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P2093

Attardi LD

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Chen S

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Jacks T

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Miller A

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Mulligan GJ

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Sage J

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Theodorou E

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Williams B

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P2860

Growth suppression by p16ink4 requires functional retinoblastoma protein

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

The retinoblastoma protein and cell cycle control

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

The regulation of E2F by pRB-family proteins

Cancer cell cycles

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

G1 events and regulation of cell proliferation

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3037-3050

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10.1101/GAD.843200

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317090

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