Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue. - Wikidata - wikimedia - TriplyDB

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue.

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue.

http://www.wikidata.org/entity/Q35227331

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The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction Visualizing functional motions of membrane transporters with molecular dynamics simulations Nonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substrates Ultra-stable organic fluorophores for single-molecule research How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters Induced pluripotent stem cell (iPSCs) and their application in immunotherapy Pluripotent stem cells in regenerative medicine: challenges and recent progress Shedding light on protein folding, structural and functional dynamics by single molecule studies The immunogenicity of cells derived from induced pluripotent stem cells Induced pluripotent stem cells in hematology: current and future applications Spontaneous inward opening of the dopamine transporter is triggered by PIP2-regulated dynamics of the N-terminus A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.Neurotransmitter and psychostimulant recognition by the dopamine transporter.Complete mapping of substrate translocation highlights the role of LeuT N-terminal segment in regulating transport cycle Single Enzyme Experiments Reveal a Long-Lifetime Proton Leak State in a Heme-Copper Oxidase Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue Insights into transport mechanism from LeuT engineered to transport tryptophan X-ray structures of LeuT in substrate-free outward-open and apo inward-open states Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context Structural evidence for functional lipid interactions in the betaine transporter BetP Molecular mechanism of ligand recognition by membrane transport protein, Mhp1 Retinal pigment epithelium transplantation: concepts, challenges, and future prospects The bright future of single-molecule fluorescence imaging Transient formation of water-conducting states in membrane transporters The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors Mapping Cholesterol Interaction Sites on Serotonin Transporter through Coarse-Grained Molecular Dynamics Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR 13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1.A conserved salt bridge between transmembrane segments 1 and 10 constitutes an extracellular gate in the dopamine transporter Navigating Membrane Protein Structure, Dynamics, and Energy Landscapes Using Spin Labeling and EPR Spectroscopy.Mapping membrane protein structure with fluorescence.A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters.Identification of novel inhibitors of the amino acid transporter B0 AT1 (SLC6A19), a potential target to induce protein restriction and to treat type 2 diabetes.Correlating charge movements with local conformational changes of a Na(+)-coupled cotransporter De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder Understanding the roadmaps to induced pluripotency.Conformational dynamics of ligand-dependent alternating access in LeuT.Not just an oil slick: how the energetics of protein-membrane interactions impacts the function and organization of transmembrane proteins.An N-terminal threonine mutation produces an efflux-favorable, sodium-primed conformation of the human dopamine transporter Molecular modeling and ligand docking for solute carrier (SLC) transporters

P2860

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P2860

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue.

http://www.wikidata.org/entity/Q35227331

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Substrate-modulated gating dyn ...... smitter transporter homologue.

@ast

Substrate-modulated gating dyn ...... smitter transporter homologue.

@en

type

label

Substrate-modulated gating dyn ...... smitter transporter homologue.

@ast

Substrate-modulated gating dyn ...... smitter transporter homologue.

@en

prefLabel

Substrate-modulated gating dyn ...... smitter transporter homologue.

@ast

Substrate-modulated gating dyn ...... smitter transporter homologue.

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P2860

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Substrate-modulated gating dyn ...... smitter transporter homologue.

@en

P2093

Daniel S Terry

http://www.w3.org/2001/XMLSchema#string

Harel Weinstein

http://www.w3.org/2001/XMLSchema#string

Jonathan A Javitch

http://www.w3.org/2001/XMLSchema#string

Lei Shi

http://www.w3.org/2001/XMLSchema#string

Matthias Quick

http://www.w3.org/2001/XMLSchema#string

Scott C Blanchard

http://www.w3.org/2001/XMLSchema#string

Yongfang Zhao

http://www.w3.org/2001/XMLSchema#string

P2860

Plasma membrane monoamine transporters: structure, regulation and function

LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake

Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures

Neurotransmitter transporters and their impact on the development of psychopharmacology

A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters

A competitive inhibitor traps LeuT in an open-to-out conformation.

Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

A rapid, sensitive, and specific method for the determination of protein in dilute solution

P2888

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109-113

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scholarly article

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10.1038/NATURE09971

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P433

7349

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474

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2011-04-24T00:00:00Z

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51073129

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1002155626

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21516104

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neurotransmitter

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3178346

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