Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence - Wikidata - wikimedia - TriplyDB

Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence

Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence

http://www.wikidata.org/entity/Q35228379

about

The evolution within us Broadly neutralizing antibodies against influenza virus and prospects for universal therapies Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements The hemagglutinin of the influenza A(H1N1)pdm09 is mutating towards stability.Longitudinal analysis of the peripheral B cell repertoire reveals unique effects of immunization with a new influenza virus strain.Design and Characterization of a Computationally Optimized Broadly Reactive Hemagglutinin Vaccine for H1N1 Influenza Viruses.H7N9 influenza virus neutralizing antibodies that possess few somatic mutations Investigating the effect of AS03 adjuvant on the plasma cell repertoire following pH1N1 influenza vaccination Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses Back to the future: recombinant polyclonal antibody therapeutics.Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications.The promise and challenge of high-throughput sequencing of the antibody repertoire.Challenges of selecting seasonal influenza vaccine strains for humans with diverse pre-exposure histories.Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season.Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods.Identification of antigen-specific B cell receptor sequences using public repertoire analysis.Genetic measurement of memory B-cell recall using antibody repertoire sequencing.The application of next generation sequencing to the understanding of antibody repertoires.Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus.Focused antibody response to influenza linked to antigenic drift Lower IgG somatic hypermutation rates during acute dengue virus infection is compatible with a germinal center-independent B cell response.Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses.Statistical inference of a convergent antibody repertoire response to influenza vaccine Lineage structure of the human antibody repertoire in response to influenza vaccination.Random yet deterministic: convergent immunoglobulin responses to influenza.De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts.Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.Impact of new sequencing technologies on studies of the human B cell repertoire.Sequencing the functional antibody repertoire--diagnostic and therapeutic discovery.Restricted, canonical, stereotyped and convergent immunoglobulin responses.Low frequency of broadly neutralizing HIV antibodies during chronic infection even in quaternary epitope targeting antibodies containing large numbers of somatic mutations.High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans.Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design.Universal flu vaccines: primum non nocere.

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Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence

http://www.wikidata.org/entity/Q35228379

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2011 nî lūn-bûn

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Epitope-specific human influen ...... ce and interclonal convergence

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Epitope-specific human influen ...... ce and interclonal convergence

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Epitope-specific human influen ...... ce and interclonal convergence

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Journal of Immunology

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Epitope-specific human influen ...... ce and interclonal convergence

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Bryan S Briney

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Chelsey J Huffman

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Jens C Krause

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Scott A Smith

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Tshidi Tsibane

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P2860

Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

Antibody recognition of a highly conserved influenza virus epitope

Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41

An Insertion Mutation That Distorts Antibody Binding Site Architecture Enhances Function of a Human Antibody

In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

The swine flu episode and the fog of epidemics.

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James E. Crowe Jr.

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Terrence M Tumpey

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51608683

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