Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein.
about
Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicityNonstructural protein 3 of hepatitis C virus blocks the distribution of the free catalytic subunit of cyclic AMP-dependent protein kinaseConstitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasiaMechanisms of cell transformation by papillomavirus E5 proteins.Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor.The bovine papillomavirus E5 protein requires a juxtamembrane negative charge for activation of the platelet-derived growth factor beta receptor and transformation of C127 cells.New concepts on the role of human papillomavirus in cell cycle regulation.Structural role of the conserved cysteines in the dimerization of the viral transmembrane oncoprotein E5.The E5 proteinsMultiple transmembrane amino acid requirements suggest a highly specific interaction between the bovine papillomavirus E5 oncoprotein and the platelet-derived growth factor beta receptor.Viral miniproteinsPapillomavirus E5: the smallest oncoprotein with many functions.Mutational analysis of the interaction between the bovine papillomavirus E5 transforming protein and the endogenous beta receptor for platelet-derived growth factor in mouse C127 cells.Mutational analysis of the beta-type platelet-derived growth factor receptor defines the site of interaction with the bovine papillomavirus type 1 E5 transforming protein.Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes.Identification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein.Hydrophobic Mismatch Drives the Interaction of E5 with the Transmembrane Segment of PDGF Receptor.Transmembrane domain sequence requirements for activation of the p185c-neu receptor tyrosine kinase.Modulation of cell function by small transmembrane proteins modeled on the bovine papillomavirus E5 protein.Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling.A single amino acid substitution converts a transmembrane protein activator of the platelet-derived growth factor β receptor into an inhibitor.The bovine papillomavirus E5 protein and the PDGF beta receptor: it takes two to tango.E5 oncoprotein retained in the endoplasmic reticulum/cis Golgi still induces PDGF receptor autophosphorylation but does not transform cellsCompensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor β receptor reveal a complex direct transmembrane interaction.Role of glutamine 17 of the bovine papillomavirus E5 protein in platelet-derived growth factor beta receptor activation and cell transformation.Failure of the bovine papillomavirus to transform mouse embryo fibroblasts with a targeted disruption of the insulin-like growth factor I receptor genes.Molecular examination of the transmembrane requirements of the platelet-derived growth factor beta receptor for a productive interaction with the bovine papillomavirus E5 oncoprotein.Protein kinase C recognizes the protein kinase A-binding motif of nonstructural protein 3 of hepatitis C virus.In vitro dimerization of the bovine papillomavirus E5 protein transmembrane domain.Two transmembrane dimers of the bovine papillomavirus E5 oncoprotein clamp the PDGF β receptor in an active dimeric conformation.
P2860
Q24645473-287FE223-F508-4622-8AEC-EEA0BAEAD997Q27480805-B16D6EAC-F3B4-4450-8351-16F7E7BE5FF8Q28640044-37DB9A2F-F0A8-4F86-852A-D9855F517EC9Q33183198-88B85106-1FDC-4235-A536-4EAA6648A50BQ33482628-B52EF36F-B2E9-4BAE-BCB7-6931963B859DQ33644980-653A9C19-9A21-4906-B3CB-3B15F4C57C51Q33708666-0F9F1AF1-5915-4464-A42F-031E8F565A2BQ34134605-B9C5E77B-D08D-4809-B675-AAD57A03ABFBQ34754347-7FBEDC7C-4CF4-4261-AEA6-9A42210D9874Q35000599-49306E15-04FD-4E9F-92A7-92C12A9E79B1Q35151120-78AABE13-CE4E-4B26-BCB8-14A2963E33D3Q35642759-7C270766-DF3D-44CC-9570-478EC92BA158Q35846414-D1C038D9-0B4D-4A1E-93E7-1DC61AC626FCQ35849030-4E87E48C-74E4-4283-8C52-F5C2020A99C9Q35877839-F1D77581-0431-44FE-8B46-80EB25981D9EQ35895171-A34CDA59-E80F-42A2-9147-3021D9E8EEF7Q35990329-5F8ABFDF-305A-43EA-9C8D-A3A758ED4F8FQ36274097-DA2CA609-9564-426A-BBC5-18E10DFC5267Q36318177-E5AC211B-AC93-486D-821E-31603971D9C5Q36550896-D410A38F-F7B3-4EB9-A11B-9B6858EECE9DQ37189482-2464F1A9-C245-412B-BF70-794B06019244Q37319770-A2CA25A3-9159-43A9-9055-FC3986DB8C14Q37619573-DA9AABD7-ED33-40E4-8006-460E0C16897FQ39113585-1DB13C34-60C8-483D-880D-35AC88A44D49Q39582036-92DC4955-6092-4C26-A9E6-667040E81666Q39871445-F6FB8F8C-3375-43FA-9F45-F3A4FA1D6AAEQ40701066-05C5D152-4A96-4CBE-90B2-8916B951867CQ42995517-E1C74463-A2EC-49C9-976F-D230C2D267CBQ43092375-7D69AD19-3E0F-47FA-A88B-057FA7160BEAQ46179447-29321BC7-934E-4C86-AF84-97CE574BBB47
P2860
Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Cellular transformation by a t ...... papillomavirus E5 oncoprotein.
@ast
Cellular transformation by a t ...... papillomavirus E5 oncoprotein.
@en
type
label
Cellular transformation by a t ...... papillomavirus E5 oncoprotein.
@ast
Cellular transformation by a t ...... papillomavirus E5 oncoprotein.
@en
prefLabel
Cellular transformation by a t ...... papillomavirus E5 oncoprotein.
@ast
Cellular transformation by a t ...... papillomavirus E5 oncoprotein.
@en
P2093
P2860
P356
P1476
Cellular transformation by a t ...... papillomavirus E5 oncoprotein.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.11.4634
P407
P577
1994-05-01T00:00:00Z