Impact of chromatin structure on sequence variability in the human genome.
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Chromatin structure is distinct between coding and non-coding single nucleotide polymorphismsGenome-wide prediction of cancer driver genes based on SNP and cancer SNV dataNucleosomes shape DNA polymorphism and divergence.Distinct roles for histone chaperones in the deposition of Htz1 in chromatinHeterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.A histone arginine methylation localizes to nucleosomes in satellite II and III DNA sequences in the human genomeGenomic variation and its impact on gene expression in Drosophila melanogaster.Nucleoid-associated proteins affect mutation dynamics in E. coli in a growth phase-specific mannerH2A.Z nucleosome positioning has no impact on genetic variation in Drosophila genomeEvidence for evolutionary and nonevolutionary forces shaping the distribution of human genetic variants near transcription start sites.Conserved substitution patterns around nucleosome footprints in eukaryotes and Archaea derive from frequent nucleosome repositioning through evolution.The pattern of DNA cleavage intensity around indelsApoptotic lymphocytes of H. sapiens lose nucleosomes in GC-rich promoters.On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Widespread signatures of recent selection linked to nucleosome positioning in the human lineage.Nucleosome Organization in Human Embryonic Stem CellsIncreasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact.The effects of chromatin organization on variation in mutation rates in the genome.Associations between nucleosome phasing, sequence asymmetry, and tissue-specific expression in a set of inbred Medaka speciesNucleosome positioning: bringing order to the eukaryotic genome.Evidence of selection for an accessible nucleosomal array in humanExtremely Rare Polymorphisms in Saccharomyces cerevisiae Allow Inference of the Mutational SpectrumFacilitation of base excision repair by chromatin remodeling.Epigenetics in the human brainEffects of DNA Methylation and Chromatin State on Rates of Molecular Evolution in InsectsGenome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools.The topography of mutational processes in breast cancer genomes.The landscape of microsatellite instability in colorectal and endometrial cancer genomes.Chromatin remodeling at DNA double-strand breaks.Fuzziness and noise in nucleosomal architecture.Nucleotide excision repair is impaired by binding of transcription factors to DNA.Genomics of behavioral diseases.Human-specific CpG "beacons" identify loci associated with human-specific traits and disease.Reduced mutation rate in exons due to differential mismatch repair.
P2860
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P2860
Impact of chromatin structure on sequence variability in the human genome.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Impact of chromatin structure on sequence variability in the human genome.
@ast
Impact of chromatin structure on sequence variability in the human genome.
@en
type
label
Impact of chromatin structure on sequence variability in the human genome.
@ast
Impact of chromatin structure on sequence variability in the human genome.
@en
prefLabel
Impact of chromatin structure on sequence variability in the human genome.
@ast
Impact of chromatin structure on sequence variability in the human genome.
@en
P2093
P2860
P356
P1476
Impact of chromatin structure on sequence variability in the human genome.
@en
P2093
Michael Y Tolstorukov
Natalia Volfovsky
Peter J Park
Robert M Stephens
P2860
P2888
P304
P356
10.1038/NSMB.2012
P577
2011-03-13T00:00:00Z