On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine. - Wikidata - wikimedia - TriplyDB

On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine.

On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine.

http://www.wikidata.org/entity/Q35358460

about

Selective in vitro and in vivo activities of 5-(2-haloalkyl)pyrimidine nucleoside analogs, particularly 5-(2-chloroethyl)-2'-deoxyuridine, against herpes simplex virus Antiherpesvirus action of atropine In vitro susceptibility of varicella-zoster virus to E-5-(2-bromovinyl)-2'-deoxyuridine and related compounds Inhibitory effect of E-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil on herpes simplex virus replication and DNA synthesis A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2 Susceptibility of recent clinical isolates of herpes simplex virus to 5-ethyl-2'-deoxyuridine: preferential inhibition of herpes simplex virus type 2 9-(3,4-dihydroxybutyl)guanine, a new inhibitor of herpesvirus multiplication Antiviral activity of the 3'-amino derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine Furano pyrimidines as novel potent and selective anti-VZV agents.Bromovinyldeoxyuridine and interferon treatment in ulcerative herpetic keratitis: a double masked study Randomised double-blind trial of bromovinyldeoxyuridine (BVDU) and trifluorothymidine (TFT) in dendritic corneal ulceration Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics.Regeneration of the antiviral drug (E)-5-(2-bromovinyl)-2'-deoxyuridine in vivo.In search of a selective antiviral chemotherapy.Pharmacokinetics and metabolism of E-5-(2-[131I]iodovinyl)-2'-deoxyuridine in dogs Possible molecular basis for antiviral activity of certain 5-substituted deoxyuridines.Effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine on synthesis of herpes simplex virus type 1-specific polypeptides Identification and some properties of a unique DNA polymerase from cells infected with human B-lymphotropic virus.Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus Analysis of the herpes simplex virus genome during in vitro latency in human diploid fibroblasts and rat sensory neurons.Alterations in substrate specificity and physicochemical properties of deoxythymidine kinase of a drug-resistant herpes simplex virus type 1 mutant.Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase Herpes simplex virus latency in isolated human neurons.Design, synthesis, and biological evaluation of unconventional aminopyrimidine, aminopurine, and amino-1,3,5-triazine methyloxynucleosides.Metabolic fate of (E)-5-(2-bromovinyl)-2'-deoxyuridine in herpes simplex virus- and mock-infected cells.Specific targets for antiviral drugs.Properties of a novel thymidine kinase induced by an acyclovir-resistant herpes simplex virus type 1 mutant.Problems associated with the use of (E)-5-(2-bromovinyl)-2'-deoxyuridine for typing herpes simplex virus.Modified polynucleotides. VI. Properties of a synthetic DNA containing the anti-herpes agent (E)-5-(2-bromovinyl)-2'-deoxyuridine.(E)-5-(2-bromovinyl)-2'-deoxyuridine-5'-triphosphate as a DNA polymerase substrate.Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine.Inhibition of glycosylation of bovine herpesvirus 1 glycoproteins by the thymidine analog (E)-5-(2 Bromovinyl)-2'-deoxyuridine Synthesis and anti-herpetic activity of phosphoramidate ProTides.Treatment of experimental herpes simplex virus encephalitis with (E)-5-(2-bromovinyl)-2'-deoxyuridine in mice.cis-trans-isomerization of [E]-5-(2-bromovinyl)-2,2'-anhydrouridine in vivo in rats.Inhibitory activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine on the salmonid herpesviruses, Oncorhynchus masou virus (OMV) and Herpesvirus salmonis.

P2860

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P2860

On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine.

http://www.wikidata.org/entity/Q35358460

description

1981 nî lūn-bûn

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1981 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1981 թվականի մայիսին հրատարակված գիտական հոդված

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1981年の論文

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1981年論文

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1981年論文

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1981年論文

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1981年论文

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On the mechanism of selective ...... 2-bromovinyl)-2'-deoxyuridine.

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On the mechanism of selective ...... 2-bromovinyl)-2'-deoxyuridine.

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On the mechanism of selective ...... 2-bromovinyl)-2'-deoxyuridine.

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On the mechanism of selective ...... 2-bromovinyl)-2'-deoxyuridine.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

On the mechanism of selective ...... 2-bromovinyl)-2'-deoxyuridine.

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P2093

E De Clercq

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H S Allaudeen

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J R Bertino

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J W Kozarich

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P2860

Antiviral activity of arabinosyladenine and arabinosylhypoxanthine in herpes simplex virus-infected KB cells: selective inhibition of viral deoxyribonucleic acid synthesis in synchronized suspension cultures

Specific herpes simplex virus-induced incorporation of 5-iodo-5'-amino-2',5'-dideoxyuridine into deoxyribonucleic acid

9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group

(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent

2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent

Acquisition of thymidine kinase activity by herpes simplex-infected mouse fibroblast cells.

Antiviral activity of arabinosylthymine in herpesviral replication: mechanism of action in vivo and in vitro.

Isolation of a herpesvirus-specific DNA polymerase from tissues of an American patient with Burkitt lymphoma.

DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants.

Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase.

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2698-2702

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10.1073/PNAS.78.5.2698

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5

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16930180

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6265902

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319424

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