Complement, age-related macular degeneration and a vision of the future - Wikidata - wikimedia - TriplyDB

Complement, age-related macular degeneration and a vision of the future

Complement, age-related macular degeneration and a vision of the future

http://www.wikidata.org/entity/Q35509833

about

Inflammation and its role in age-related macular degeneration Complement activation in the context of stem cells and tissue repair Systems genetics for drug target discovery Complement regulator CD46: genetic variants and disease associations Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis Complement: a key system for immune surveillance and homeostasis Retinal prosthesis Using current data to define new approach in age related macular degeneration: need to accelerate translational research.Systemic complement inhibition with eculizumab for geographic atrophy in age-related macular degeneration: the COMPLETE study A Review of Current and Future Management of Geographic Atrophy.Activation of P2X receptors induces apoptosis in human retinal pigment epithelium Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases.Fundus autofluorescence and spectral-domain optical coherence tomography characteristics in a rapidly progressing form of geographic atrophy.Mutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma Dry age-related macular degeneration: A currently unmet clinical need.Genetics of age-related macular degeneration: current concepts, future directions.The role of anti-inflammatory agents in age-related macular degeneration (AMD) treatment Risk- and non-risk-associated variants at the 10q26 AMD locus influence ARMS2 mRNA expression but exclude pathogenic effects due to protein deficiency.Race- and sex-related differences in retinal thickness and foveal pit morphology.Decay accelerating factor (CD55)-mediated attenuation of complement: therapeutic implications for age-related macular degeneration.Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death.Dark matters in AMD genetics: epigenetics and stochasticity Complement gene expression and regulation in mouse retina and retinal pigment epithelium/choroid.A pilot quantitative study of topographic correlation between reticular pseudodrusen and the choroidal vasculature using en face optical coherence tomography.C2 rs547154 polymorphism and polypoidal choroidal vasculopathy susceptibility: a meta-analysis.Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration.Role of complement and complement regulatory proteins in the complications of diabetes Association Study of Mannose-Binding Lectin Levels and Genetic Variants in Lectin Pathway Proteins with Susceptibility to Age-Related Macular Degeneration: A Case-Control Study.Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degeneration Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD)Management of retinal vascular diseases: a patient-centric approach.Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks.Predictive, preventive and personalised medicine for age-related macular degeneration A novel role of complement in retinal degeneration.A2E accumulation influences retinal microglial activation and complement regulation Susceptibility to advanced age-related macular degeneration and alleles of complement factor H, complement factor B, complement component 2, complement component 3, and age-related maculopathy susceptibility 2 genes in a Mexican population.Recent advances in the management of dry age-related macular degeneration: A review.Manipulating the mediator: modulation of the alternative complement pathway C3 convertase in health, disease and therapy.Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration

P2860

Q26768520-EA34A9B1-02AC-4A92-B71C-79C89FD9535C Q26782203-8356000F-0EE2-4741-98DE-7E23FD6FA17A Q27012769-56FF85A9-B63C-4EE1-8E3E-5DD202AA8815 Q28263110-D747127D-07D2-4B16-B106-0FB3C2ACA06A Q28551885-4D3F0491-ED61-46B8-952C-7987467E0D04 Q29615484-21477281-4446-44EC-8F13-FDDB5BED31C7 Q30626831-3D6A401D-2E2F-4F57-B41E-B25891CE45D8 Q30843382-E24225E4-4703-4C91-A28B-74B74ABA219B Q33586908-B64E753E-38BD-4E67-8BFC-C72349F69B14 Q33740158-482FE06C-2C62-4A35-9B2C-78B635798BD2 Q33744909-801B016F-A512-4C91-B6A2-9106F595B6DC Q33747656-27956114-8A34-40FE-B4B4-9D8E88429DC3 Q33817842-F72A06BE-349A-470D-A6B5-FB9E234C3B84 Q33838251-6902DCD7-549E-41F1-BCD8-1928F71DC742 Q34378033-CB5A6278-E3A4-489C-AC77-10EED185A708 Q34565573-3E8FB3CD-F1E1-4B2C-869F-EA2A1B604383 Q34605896-A5DC6F06-5A9B-4C2D-8760-B0D228C64C60 Q34627058-5C447D87-B1AF-40BB-9534-C9BABB25A2E3 Q34646882-C0CF294B-4934-4541-9B2C-D5B1DC8A2C24 Q34662323-D5DB1BBF-99EF-42E5-A54E-3B8A60D353C4 Q34738110-308B53B3-48ED-4A85-A8A6-CF56AC8E4305 Q35005822-22BAB77F-8314-4EA1-ACA1-B5F0A329D258 Q35068037-3C39EEE1-53D1-489D-8C4B-4C8EA2507A37 Q35128137-2DC00B9C-9A29-41D0-A75B-19AD7F3000BD Q35138698-8E761748-1079-426D-B2EC-DBC7FEF0EAE8 Q35175046-C9FD2FA8-40D2-4E02-92F0-205E51E28451 Q35546888-9ABA9326-87B8-46A1-830B-2DF760E6EEBE Q35657115-AFBE7503-3F58-4366-9AD4-9EFD84874778 Q35710508-B3A5D173-54E2-4357-A46C-C2E2AE89363B Q35819298-D3CC4893-4A4A-4F7D-9257-87DFCAF70896 Q35887465-1CCAEBE7-558F-4FC2-ACAB-C89995F32E61 Q35909406-3D479BF7-C8AD-4C30-A1D6-310B4EE9FD9F Q36023209-94A9B2DC-6D16-48D1-8D1E-04258D0B460F Q36117612-109B42EC-5521-4702-96A9-3CBC8CB701BB Q36164495-1A7112BB-A6F0-49C6-BDEF-77CBCF92741D Q36346763-4420D52D-F2DD-4ABC-A9A5-7F677286EF04 Q36350405-3CAEFA87-1C0B-4D48-BDE4-5B56657B3E79 Q36377333-445E9DB9-1359-4243-99F8-D2FE1030A8E2 Q36463266-55387B54-8C8E-4AF9-AF6D-63D6B9E115C2 Q36477011-FA3984E9-A601-4521-9CCA-2B86D5572C41

P2860

Complement, age-related macular degeneration and a vision of the future

http://www.wikidata.org/entity/Q35509833

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մարտին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Complement, age-related macular degeneration and a vision of the future

@ast

Complement, age-related macular degeneration and a vision of the future

@en

type

label

Complement, age-related macular degeneration and a vision of the future

@ast

Complement, age-related macular degeneration and a vision of the future

@en

prefLabel

Complement, age-related macular degeneration and a vision of the future

@ast

Complement, age-related macular degeneration and a vision of the future

@en

P1433

Q35509833-2B33058C-E5BE-43B3-8127-7CF9CB0ED515

P1476

Q35509833-167B34C1-6B0C-47B7-834E-AB9B92B1BD22

P2093

Q35509833-13FDCB3D-9603-4DDF-BDD9-4CC1E810C2CA

Q35509833-186763FF-AC68-47DA-8EC6-5770AC381924

Q35509833-5AC53069-2C5E-4DC0-84B0-0595A1F7B023

Q35509833-B6AD7195-D5E0-48D1-A41B-30ABAAB44B6B

Q35509833-EFC327A7-7AD7-40AB-ADE1-419749811B10

P2860

Q35509833-00E3A2B5-6BBC-455E-AB34-56AE164A4350

Q35509833-0288F447-D6C8-4EC6-8C3E-D308140795A1

Q35509833-055265E9-96C4-49F7-85BA-A1F49D2D2C0D

Q35509833-088E1B93-0B64-412B-B35D-90617032129A

Q35509833-0970FF6F-8DA9-40ED-BA92-8396F870676D

Q35509833-0ACCF80A-FA35-457F-BC1B-9FF99A460016

Q35509833-1145B13F-1147-4C95-A524-355455CB1F54

Q35509833-12968BF8-5CB8-481E-A62B-CD372B972E8B

Q35509833-13C7AA5C-0864-44A1-91CD-8B2020044F56

Q35509833-15559626-CA8F-4A58-BED6-8D2A270C0B8D

P304

Q35509833-3E9733B3-EBD2-4EC1-BFA7-08B776E5A714

P31

Q35509833-5FA0D683-E7F2-4D0A-BB9A-4FBBB6BBFA4C

P356

Q35509833-B035724F-4992-4DDC-ABAA-FCD29CCE9D72

P407

Q35509833-3D22ECA2-FEBD-4824-BC79-C0C68AD830D0

P433

Q35509833-7C5F8389-6966-42DD-9945-3D2C1FED97F4

P478

Q35509833-7468534C-0002-47DD-B314-D9A5182165E4

P577

Q35509833-D83EBED5-5251-4993-A840-702B3CC5F940

P698

Q35509833-F3762802-68C6-4FA1-AB6C-556F067DECC2

P932

Q35509833-B670222E-DB28-4205-A0D1-6ED7D2602AC5

P356

ARCHOPHTHALMOL.2010.18

P1433

JAMA Ophthalmology

P1476

Complement, age-related macular degeneration and a vision of the future

@en

P2093

Eric N Brown

http://www.w3.org/2001/XMLSchema#string

Gregory S Hageman

http://www.w3.org/2001/XMLSchema#string

Jared R Jackson

http://www.w3.org/2001/XMLSchema#string

Karen M Gehrs

http://www.w3.org/2001/XMLSchema#string

Rando Allikmets

http://www.w3.org/2001/XMLSchema#string

P2860

Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA

Implications of the serine protease HtrA1 in amyloid precursor protein processing

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

Susceptibility genes for age-related maculopathy on chromosome 10q26.

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9

Complement factor H polymorphism in age-related macular degeneration

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications

An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

P304

349-358

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1001/ARCHOPHTHALMOL.2010.18

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

128

http://www.w3.org/2001/XMLSchema#string

P577

2010-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20212207

http://www.w3.org/2001/XMLSchema#string

P932

4405117

http://www.w3.org/2001/XMLSchema#string