The immediate-early 63 protein of Varicella-Zoster virus: analysis of functional domains required for replication in vitro and for T-cell and skin tropism in the SCIDhu model in vivo.
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Dissecting the Molecular Mechanisms of the Tropism of Varicella-Zoster Virus for Human T CellsGenome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factorThe varicella-zoster virus immediate-early 63 protein affects chromatin-controlled gene transcription in a cell-type dependent mannerRole of the varicella-zoster virus gene product encoded by open reading frame 35 in viral replication in vitro and in differentiated human skin and T cells in vivo.Regions of the varicella-zoster virus open reading frame 63 latency-associated protein important for replication in vitro are also critical for efficient establishment of latency.Varicella-zoster virus infection of human dorsal root ganglia in vivo.Molecular mechanisms of varicella zoster virus pathogenesis.Varicella-zoster virus T cell tropism and the pathogenesis of skin infectionVaricella-Zoster virus pathogenesis and immunobiology: new concepts emerging from investigations with the SCIDhu mouse model.Identification of phosphorylated residues on varicella-zoster virus immediate-early protein ORF63.Mutational analysis of the varicella-zoster virus ORF62/63 intergenic regionMouse models with human immunity and their application in biomedical research.Varicella zoster virus latency.Mutagenesis of varicella-zoster virus glycoprotein I (gI) identifies a cysteine residue critical for gE/gI heterodimer formation, gI structure, and virulence in skin cells.Essential functions of the unique N-terminal region of the varicella-zoster virus glycoprotein E ectodomain in viral replication and in the pathogenesis of skin infectionORF66 protein kinase function is required for T-cell tropism of varicella-zoster virus in vivoVaricella-Zoster virus IE63, a major viral latency protein, is required to inhibit the alpha interferon-induced antiviral responseRecombinant monoclonal antibody recognizes a unique epitope on varicella-zoster virus immediate-early 63 protein.Cellular and viral factors regulate the varicella-zoster virus gE promoter during viral replication.A varicella-zoster virus mutant impaired for latency in rodents, but not impaired for replication in cell cultureThe varicella-zoster virus genomeVaricella-zoster virus immediate-early 63 protein interacts with human antisilencing function 1 protein and alters its ability to bind histones h3.1 and h3.3.Phosphorylation of the nuclear form of varicella-zoster virus immediate-early protein 63 by casein kinase II at serine 186.Differential requirement for cell fusion and virion formation in the pathogenesis of varicella-zoster virus infection in skin and T cells.Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivo.Insights into the function of tegument proteins from the varicella zoster virus.ORF11 protein interacts with the ORF9 essential tegument protein in varicella-zoster virus infectionNuclear import of the varicella-zoster virus latency-associated protein ORF63 in primary neurons requires expression of the lytic protein ORF61 and occurs in a proteasome-dependent manner.The varicella-zoster virus (VZV) ORF9 protein interacts with the IE62 major VZV transactivator.Varicella-zoster virus IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity.Replication of varicella-zoster virus in human skin organ cultureVaricella-zoster virus IE63 protein represses the basal transcription machinery by disorganizing the pre-initiation complex.The replication cycle of varicella-zoster virus: analysis of the kinetics of viral protein expression, genome synthesis, and virion assembly at the single-cell level.Development of recombinant varicella-zoster viruses expressing luciferase fusion proteins for live in vivo imaging in human skin and dorsal root ganglia xenografts.
P2860
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P2860
The immediate-early 63 protein of Varicella-Zoster virus: analysis of functional domains required for replication in vitro and for T-cell and skin tropism in the SCIDhu model in vivo.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The immediate-early 63 protein ...... m in the SCIDhu model in vivo.
@ast
The immediate-early 63 protein ...... m in the SCIDhu model in vivo.
@en
type
label
The immediate-early 63 protein ...... m in the SCIDhu model in vivo.
@ast
The immediate-early 63 protein ...... m in the SCIDhu model in vivo.
@en
prefLabel
The immediate-early 63 protein ...... m in the SCIDhu model in vivo.
@ast
The immediate-early 63 protein ...... m in the SCIDhu model in vivo.
@en
P2093
P2860
P1433
P1476
The immediate-early 63 protein ...... sm in the SCIDhu model in vivo
@en
P2093
Ann M Arvin
Christoph Bagowski
Hideki Ito
Klaus Fabel
Leigh Zerboni
Marvin Sommer
William Ruyechan
P2860
P304
P356
10.1128/JVI.78.3.1181-1194.2004
P407
P577
2004-02-01T00:00:00Z