Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes.
about
Inactivation of p53 rescues the maintenance of high risk HPV DNA genomes deficient in expression of E6Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteinsRole of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31Epithelial cell migration requires the interaction between the vimentin and keratin intermediate filamentsThe Role of the DNA Damage Response throughout the Papillomavirus Life CyclePapillomavirus E6 oncoproteins.Papillomavirus E6 PDZ interactions can be replaced by repression of p53 to promote episomal human papillomavirus genome maintenanceInterference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1.Human papillomavirus type 16 E7 binds to E2F1 and activates E2F1-driven transcription in a retinoblastoma protein-independent manner.Papillomavirus interaction with cellular chromatin.Variant upstream regulatory region sequences differentially regulate human papillomavirus type 16 DNA replication throughout the viral life cycle.Expression of the HPV18/E6 oncoprotein induces DNA damage.Epigenetic repression of E-cadherin by human papillomavirus 16 E7 protein.Cellular changes induced by low-risk human papillomavirus type 11 in keratinocytes that stably maintain viral episomesEarly polyadenylation signals of human papillomavirus type 31 negatively regulate capsid gene expression.Persistence of viral DNA in the epithelial basal layer suggests a model for papillomavirus latency following immune regression.HPV episome levels are potently decreased by pyrrole-imidazole polyamides.Human papillomavirus type 16 E1circumflexE4 contributes to multiple facets of the papillomavirus life cycle.The E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradationVariations in the association of papillomavirus E2 proteins with mitotic chromosomesNuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance.Pathogenesis of human papillomaviruses in differentiating epithelia.Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes.Long-term effect of interferon on keratinocytes that maintain human papillomavirus type 31.Biological activities and molecular targets of the human papillomavirus E7 oncoprotein.The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells.Persistence of human papillomavirus infection: keys to malignant progressionDeregulation of eIF4E: 4E-BP1 in differentiated human papillomavirus-containing cells leads to high levels of expression of the E7 oncoprotein.Human papillomavirus type 31 replication modes during the early phases of the viral life cycle depend on transcriptional and posttranscriptional regulation of E1 and E2 expression.Nonconserved lysine residues attenuate the biological function of the low-risk human papillomavirus E7 proteinGenomic Instability Induced By Human Papillomavirus Oncogenes.Brd4 is displaced from HPV replication factories as they expand and amplify viral DNASmall molecule inhibitors of human papillomavirus protein - protein interactions.Replication and partitioning of papillomavirus genomes.p63 is necessary for the activation of human papillomavirus late viral functions upon epithelial differentiation.The E7 open reading frame acts in cis and in trans to mediate differentiation-dependent activities in the human papillomavirus type 16 life cycle.Recent Insights into the Control of Human Papillomavirus (HPV) Genome Stability, Loss, and Degradation.Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulatorsThe Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy.Productive Lifecycle of Human Papillomaviruses that Depends Upon Squamous Epithelial Differentiation.
P2860
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P2860
Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Human papillomavirus type 31 o ...... in normal human keratinocytes.
@ast
Human papillomavirus type 31 o ...... in normal human keratinocytes.
@en
type
label
Human papillomavirus type 31 o ...... in normal human keratinocytes.
@ast
Human papillomavirus type 31 o ...... in normal human keratinocytes.
@en
prefLabel
Human papillomavirus type 31 o ...... in normal human keratinocytes.
@ast
Human papillomavirus type 31 o ...... in normal human keratinocytes.
@en
P2093
P2860
P356
P1476
Human papillomavirus type 31 o ...... in normal human keratinocytes.
@en
P2093
J T Thomas
L A Laimins
M N Ruesch
W G Hubert
P2860
P304
P356
10.1073/PNAS.96.15.8449
P407
P577
1999-07-01T00:00:00Z