Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4.
about
Targeting NADPH oxidases for the treatment of cancer and inflammationConstitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance developmentChemical methods for the simultaneous quantitation of metabolites and proteins from single cellsReactive Oxygen Species-Mediated Mechanisms of Action of Targeted Cancer TherapyErlotinib preserves renal function and prevents salt retention in doxorubicin treated nephrotic rats.EGFR-TKI, erlotinib, causes hypomagnesemia, oxidative stress, and cardiac dysfunction: attenuation by NK-1 receptor blockadeMyD88-Dependent Signaling Decreases the Antitumor Efficacy of Epidermal Growth Factor Receptor Inhibition in Head and Neck Cancer Cells.EGFR tyrosine kinase inhibition induces autophagy in cancer cells.NADPH oxidase biology and the regulation of tyrosine kinase receptor signaling and cancer drug cytotoxicityRole of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer.NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells.EGFR inhibition induces proinflammatory cytokines via NOX4 in HNSCC.Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications.Autophagic action of new targeting agents in head and neck oncology.Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib.Induction of reactive oxygen species: an emerging approach for cancer therapy.Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4.Redox control of cancer cell destruction.DAPk silencing by DNA methylation conveys resistance to anti EGFR drugs in lung cancer cells.Targeting Oxidatively Induced DNA Damage Response in Cancer: Opportunities for Novel Cancer Therapies.Protegrin 1 Enhances Innate Cellular Defense via the Insulin-Like Growth Factor 1 Receptor PathwayMAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma
P2860
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P2860
Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Erlotinib-mediated inhibition ...... oxidative stress through NOX4.
@ast
Erlotinib-mediated inhibition ...... oxidative stress through NOX4.
@en
type
label
Erlotinib-mediated inhibition ...... oxidative stress through NOX4.
@ast
Erlotinib-mediated inhibition ...... oxidative stress through NOX4.
@en
prefLabel
Erlotinib-mediated inhibition ...... oxidative stress through NOX4.
@ast
Erlotinib-mediated inhibition ...... oxidative stress through NOX4.
@en
P2093
P2860
P1433
P1476
Erlotinib-mediated inhibition ...... oxidative stress through NOX4
@en
P2093
Amanda L Kalen
Andrean L Simons
Arlene D Parsons
Arya Sobhakumari
Francis J Miller
Kevin P Orcutt
Peter M Scarbrough
Werner W Wilke
Yueming Zhu
Zita A Sibenaller
P2860
P304
P356
10.1158/0008-5472.CAN-10-3425
P407
P577
2011-04-11T00:00:00Z