EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
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A kinase-independent role for EGF receptor in autophagy initiationEGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistancePotential Compounds for Oral Cancer Treatment: Resveratrol, Nimbolide, Lovastatin, Bortezomib, Vorinostat, Berberine, Pterostilbene, Deguelin, Andrographolide, and ColchicineChloroquine enhances gefitinib cytotoxicity in gefitinib-resistant nonsmall cell lung cancer cells.Autophagosome-mediated EGFR down-regulation induced by the CK2 inhibitor enhances the efficacy of EGFR-TKI on EGFR-mutant lung cancer cells with resistance by T790M.Maintenance of glia in the optic lamina is mediated by EGFR signaling by photoreceptors in adult Drosophila.Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines.Bystander autophagy mediated by radiation-induced exosomal miR-7-5p in non-targeted human bronchial epithelial cellsNOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells.Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications.Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer.Metformin promotes apoptosis in hepatocellular carcinoma through the CEBPD-induced autophagy pathway.EGFR inhibitors and autophagy in cancer treatment.Nrf2 but not autophagy inhibition is associated with the survival of wild-type epidermal growth factor receptor non-small cell lung cancer cells.Protein Kinase G facilitates EGFR-mediated cell death in MDA-MB-468 cells.Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer.Featured article: autophagic activation with nimotuzumab enhanced chemosensitivity and radiosensitivity of esophageal squamous cell carcinoma.EGFR Family Members' Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in Cancer.Changes in cell junctions induced by inhibition of epidermal growth factor receptor in oral squamous cell carcinoma cellsMetalloprotease-dependent activation of EGFR modulates CD44+/CD24- populations in triple negative breast cancer cells through the MEK/ERK pathway.Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia.EGFR tyrosine kinase inhibitors differentially affect autophagy in head and neck squamous cell carcinoma.Lower mRNA and protein expression levels of LC3 and Beclin1, markers of autophagy, were correlated with progression of renal clear cell carcinoma.Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking.Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and Akt.Cell death-based treatment of lung adenocarcinoma.Targeting Autophagy in ALK-Associated Cancers.Autophagy inhibition improves the cytotoxic effects of receptor tyrosine kinase inhibitors.Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis.MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells.Arsenic circumvents the gefitinib resistance by binding to P62 and mediating autophagic degradation of EGFR in non-small cell lung cancer
P2860
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P2860
EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
@ast
EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
@en
type
label
EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
@ast
EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
@en
prefLabel
EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
@ast
EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
@en
P2093
P2860
P356
P1476
EGFR tyrosine kinase inhibition induces autophagy in cancer cells.
@en
P2093
Christopher Fung
Umamaheswar Duvvuri
P2860
P304
P356
10.4161/CBT.22002
P577
2012-09-06T00:00:00Z