Hexose-6-phosphate dehydrogenase contributes to skeletal muscle homeostasis independent of 11β-hydroxysteroid dehydrogenase type 1.

Hexose-6-phosphate dehydrogenase contributes to skeletal muscle homeostasis independent of 11β-hydroxysteroid dehydrogenase type 1.

Item
http://www.wikidata.org/entity/Q35558474
11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excessBiomarkers of hypothalamic-pituitary-adrenal axis activity in mice lacking 11β-HSD1 and H6PDHLack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.Novel H6PDH mutations in two girls with premature adrenarche: 'apparent' and 'true' CRD can be differentiated by urinary steroid profiling.Genetic background (DDD/Sgn versus C57BL/6J) strongly influences postnatal growth of male mice carrying the A(y) allele at the agouti locus: identification of quantitative trait loci associated with diabetes and body weight loss.11β-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo.11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects.Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid.Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation.11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action.Cellular and genetic models of H6PDH and 11β-HSD1 function in skeletal muscle.Safety, pharmacokinetics and pharmacodynamics of BI 135585, a selective 11β-hydroxysteroid dehydrogenase-1 (HSD1) inhibitor in humans: liver and adipose tissue 11β-HSD1 inhibition after acute and multiple administrations over 2 weeks.Male 11β-HSD1 Knockout Mice Fed Trans-Fats and Fructose Are Not Protected From Metabolic Syndrome or Nonalcoholic Fatty Liver Disease.Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balance.
P2860

Hexose-6-phosphate dehydrogenase contributes to skeletal muscle homeostasis independent of 11β-hydroxysteroid dehydrogenase type 1.

Item
http://www.wikidata.org/entity/Q35558474
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@ast
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@en
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@en-gb
type
label
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@ast
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@en
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@en-gb
prefLabel
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@ast
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@en
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@en-gb
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Hexose-6-phosphate dehydrogena ...... ysteroid dehydrogenase type 1.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932