Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.
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Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-linksOxidative stress responses in Escherichia coli and Salmonella typhimuriumA structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycolBinding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion siteA Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease ComplexThe Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeastDynamic compartmentalization of base excision repair proteins in response to nuclear and mitochondrial oxidative stressDifferential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesionsEffect of thymine glycol on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase IIDNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extractsUnexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variabilityThe oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterpartsEfficient formation of the tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells.Insights into the glycosylase search for damage from single-molecule fluorescence microscopy.Synthesis and thermodynamic studies of oligonucleotides containing the two isomers of thymine glycol.Solution conformation of an oligonucleotide containing a urea deoxyribose residue in front of a thymine.The RepE initiator is a double-stranded and single-stranded DNA-binding protein that forms an atypical open complex at the onset of replication of plasmid pAMbeta 1 from Gram-positive bacteria.Two glycosylase families diffusively scan DNA using a wedge residue to probe for and identify oxidatively damaged bases.Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1.An in vitro assay for frameshift mutations: hotspots for deletions of 1 bp by Klenow-fragment polymerase share a consensus DNA sequenceMitochondrial DNA alterations and reduced mitochondrial function in agingHuman DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides.Base excision repair in a network of defence and tolerance.Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity.Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies.Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context.Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.Transcription-dependent R-loop formation at mammalian class switch sequences.Dehydration, deamination and enzymatic repair of cytosine glycols from oxidized poly(dG-dC) and poly(dI-dC)Mitochondrial longevity pathwaysA novel method for site specific introduction of single model oxidative DNA lesions into oligodeoxyribonucleotidesOxidation of DNA bases by tumor promoter-activated processes.Endonuclease III and endonuclease VIII conditionally targeted into mitochondria enhance mitochondrial DNA repair and cell survival following oxidative stress.The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structuresEscherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutantsBlockage of polymerase-catalyzed DNA chain elongation by chemically modified cytosine residues in templates and the release of blockage for readthrough.The FLP protein contacts both major and minor grooves of its recognition target sequence.Mfd is required for rapid recovery of transcription following UV-induced DNA damage but not oxidative DNA damage in Escherichia coli.Ring-opened 7-methylguanine residues in DNA are a block to in vitro DNA synthesis.Dihydrothymidine and thymidine glycol triphosphates as substrates for DNA polymerases: differential recognition of thymine C5-C6 bond saturation and sequence specificity of incorporation.
P2860
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P2860
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.
@ast
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.
@en
type
label
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.
@ast
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.
@en
prefLabel
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.
@ast
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.
@en
P2860
P356
P1476
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro
@en
P2860
P304
P356
10.1093/NAR/13.22.8035
P407
P577
1985-11-01T00:00:00Z