Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides.
about
A unique error signature for human DNA polymerase nuMouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesisPreferential formation of (5S,6R)-thymine glycol for oligodeoxyribonucleotide synthesis and analysis of drug binding to thymine glycol-containing DNA.Pathways for repairing and tolerating the spectrum of oxidative DNA lesionsA structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycolThe cis -(5 R ,6 S )-Thymine Glycol Lesion Occupies the Wobble Position When Mismatched with Deoxyguanosine in DNAYeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycolBase excision repair facilitates a functional relationship between Guanine oxidation and histone demethylationA nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycolThe N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesionsA role for DNA polymerase θ in promoting replication through oxidative DNA lesion, thymine glycol, in human cells.Variations on a theme: eukaryotic Y-family DNA polymerasesIdentification of two functional PCNA-binding domains in human DNA polymerase κEpistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage.Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells.Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenineDNA polymerases and somatic hypermutation of immunoglobulin genesBase excision repair and lesion-dependent subpathways for repair of oxidative DNA damage.Checkpoint activation regulates mutagenic translesion synthesisHuman thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair.Suffering in silence: the tolerance of DNA damage.Polymerase Bypass of N(6)-Deoxyadenosine Adducts Derived from Epoxide Metabolites of 1,3-Butadiene.Synthesis and thermodynamic studies of oligodeoxyribonucleotides containing tandem lesions of thymidine glycol and 8-oxo-2'-deoxyguanosineMass spectrometry of structurally modified DNA.Stereoselective excision of thymine glycol from oxidatively damaged DNA.Kinetics of deamination and Cu(II)/H2O2/Ascorbate-induced formation of 5-methylcytosine glycol at CpG sites in duplex DNA.DNA polymerase kappa protects human cells against MMC-induced genotoxicity through error-free translesion DNA synthesisMechanisms of base substitution mutagenesis in cancer genomes.Chemistry and structural biology of DNA damage and biological consequencesMouse models of DNA polymerases.Catalytic and non-catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses.Base excision repair of oxidative DNA damage: from mechanism to disease.Global genome removal of thymine glycol in Escherichia coli requires endonuclease III but the persistence of processed repair intermediates rather than thymine glycol correlates with cellular sensitivity to high doses of hydrogen peroxide.Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.Refolding active human DNA polymerase nu from inclusion bodies.Pyrimidine Nucleobase Radical Reactivity in DNA and RNA.Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.Mode of inhibition of short-patch base excision repair by thymine glycol within clustered DNA lesions.Translesion synthesis by POLKSynthesis of a convenient thymidine glycol phosphoramidite monomer and its site-specific incorporation into DNA fragments.
P2860
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P2860
Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@ast
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@en
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@nl
type
label
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@ast
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@en
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@nl
prefLabel
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@ast
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@en
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@nl
P2093
P2860
P356
P1476
Human DNA polymerase kappa byp ...... rporating correct nucleotides.
@en
P2093
Errol C Friedberg
Paula L Fischhaber
Susan S Wallace
Valerie L Gerlach
William J Feaver
Zafer Hatahet
P2860
P304
37604-37611
P356
10.1074/JBC.M206027200
P407
P577
2002-07-26T00:00:00Z