Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism
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Pancreatic Cancer Metabolism: Breaking It Down to Build It Back UpIncreased oxidative metabolism in the Li-Fraumeni syndromeDAMPs, ageing, and cancer: The 'DAMP Hypothesis'.Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling.Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1.Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone productionTwo-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cellsProteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblastsMitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth.Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cellsThe milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis.Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cellsMitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin.Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor α (ERRα).SIRT1 suppresses the epithelial-to-mesenchymal transition in cancer metastasis and organ fibrosis.Autophagic tumor stroma: mechanisms and roles in tumor growth and progression.Lactate transporters in the context of prostate cancer metabolism: what do we know?Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells.The Intricate Interplay between Mechanisms Underlying Aging and Cancer.Nuclear respiratory factor-1 and bioenergetics in tamoxifen-resistant breast cancer cells.New approach to generating insights for aging research based on literature mining and knowledge integration.Transmissible cancers in an evolutionary context.Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cellsA glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy.Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch.Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages.The reverse Warburg effect is likely to be an Achilles' heel of cancer that can be exploited for cancer therapy.Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs).HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia.Carnosine: can understanding its actions on energy metabolism and protein homeostasis inform its therapeutic potential?PGC1α: Friend or Foe in Cancer?
P2860
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P2860
Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Is cancer a metabolic rebellio ...... sting mitochondrial metabolism
@ast
Is cancer a metabolic rebellio ...... sting mitochondrial metabolism
@en
type
label
Is cancer a metabolic rebellio ...... sting mitochondrial metabolism
@ast
Is cancer a metabolic rebellio ...... sting mitochondrial metabolism
@en
prefLabel
Is cancer a metabolic rebellio ...... sting mitochondrial metabolism
@ast
Is cancer a metabolic rebellio ...... sting mitochondrial metabolism
@en
P2093
P2860
P50
P356
P1433
P1476
Is cancer a metabolic rebellio ...... sting mitochondrial metabolism
@en
P2093
Adam Ertel
Richard G Pestell
Stephanos Pavlides
P2860
P304
P356
10.4161/CC.11.2.19006
P50
P577
2012-01-15T00:00:00Z