Excited states of ribosome translocation revealed through integrative molecular modeling.
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Steric interactions lead to collective tilting motion in the ribosome during mRNA-tRNA translocationAllosteric control of the ribosome by small-molecule antibiotics.Interplay of the bacterial ribosomal A-site, S12 protein mutations and paromomycin binding: a molecular dynamics study.Reliable oligonucleotide conformational ensemble generation in explicit solvent for force field assessment using reservoir replica exchange molecular dynamics simulations.Differences between cotranscriptional and free riboswitch foldingThe ribosome's energy landscape: Recent insights from computationComputational Methodologies for Real-Space Structural Refinement of Large Macromolecular Complexes.Consensus among flexible fitting approaches improves the interpretation of cryo-EM data.Movement of elongation factor G between compact and extended conformations.Free-energy landscape of reverse tRNA translocation through the ribosome analyzed by electron microscopy density maps and molecular dynamics simulations.Cryo-EM of ribosomal 80S complexes with termination factors reveals the translocated cricket paralysis virus IRES.SMOG 2: A Versatile Software Package for Generating Structure-Based Models.Intermediate states during mRNA-tRNA translocation.Computational studies of molecular machines: the ribosome.Simulating movement of tRNA through the ribosome during hybrid-state formation.Reduced model captures Mg(2+)-RNA interaction free energy of riboswitchesCollective variable approaches for single molecule flexible fitting and enhanced sampling.Structural Insights into tRNA Dynamics on the Ribosome.Flexible fitting to cryo-EM density map using ensemble molecular dynamics simulations.Electron Cryo-microscopy as a Tool for Structure-Based Drug Development.Theoretical modeling of multiprotein complexes by iSPOT: Integration of small-angle X-ray scattering, hydroxyl radical footprinting, and computational docking.Molecular architecture of the ribosome-bound Hepatitis C Virus internal ribosomal entry site RNA.Tools for the Cryo-EM Gold Rush: Going from the cryo-EM map to the atomistic model.Enhanced sampling and overfitting analyses in structural refinement of nucleic acids into electron microscopy mapsThe shadow map: a general contact definition for capturing the dynamics of biomolecular folding and functionUsing enhanced sampling and structural restraints to refine atomic structures into low-resolution electron microscopy maps.Structure and mechanical properties of the ribosomal L1 stalk three-way junction.eSBMTools 1.0: enhanced native structure-based modeling tools.A fragment based method for modeling of protein segments into cryo-EM density maps.Model of ribosomal translocation coupled with intra- and inter-subunit rotations.RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.Enzymatic Activity and Thermodynamic Stability of Biliverdin IXβ Reductase Are Maintained by an Active Site Serine.Motion of transfer RNA from the A/T state into the A-site using docking and simulations.Kryo-Elektronenmikroskopie als Methode für die strukturbasierte Wirkstoffentwicklung
P2860
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P2860
Excited states of ribosome translocation revealed through integrative molecular modeling.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Excited states of ribosome translocation revealed through integrative molecular modeling.
@ast
Excited states of ribosome translocation revealed through integrative molecular modeling.
@en
type
label
Excited states of ribosome translocation revealed through integrative molecular modeling.
@ast
Excited states of ribosome translocation revealed through integrative molecular modeling.
@en
prefLabel
Excited states of ribosome translocation revealed through integrative molecular modeling.
@ast
Excited states of ribosome translocation revealed through integrative molecular modeling.
@en
P2093
P2860
P356
P1476
Excited states of ribosome translocation revealed through integrative molecular modeling.
@en
P2093
Aqeel Ahmed
Christian M T Spahn
Florence Tama
Karissa Y Sanbonmatsu
Paul C Whitford
Scott P Hennelly
P2860
P304
18943-18948
P356
10.1073/PNAS.1108363108
P407
P50
P577
2011-11-11T00:00:00Z