Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death.
about
Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in miceAxon degeneration: Molecular mechanisms of a self-destruction pathwayKynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects.Rapid in vivo forward genetic approach for identifying axon death genes in DrosophilaNMNAT: It's an NAD+ synthase… It's a chaperone… It's a neuroprotector.WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity.Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses.Screening with an NMNAT2-MSD platform identifies small molecules that modulate NMNAT2 levels in cortical neurons.Cobalamin C Deficiency Shows a Rapidly Progressing Maculopathy With Severe Photoreceptor and Ganglion Cell Loss.Protection of mouse retinal ganglion cell axons and soma from glaucomatous and ischemic injury by cytoplasmic overexpression of Nmnat1.Rescuing axons from degeneration does not affect retinal ganglion cell death.Nicotinamide mononucleotide adenylyltransferase promotes hypoxic survival by activating the mitochondrial unfolded protein response.Nmnat1 protects neuronal function without altering phospho-tau pathology in a mouse model of tauopathy.NMNATs, evolutionarily conserved neuronal maintenance factors.Caspase-6 as a novel early target in the treatment of Alzheimer's disease.Wallerian degeneration: an emerging axon death pathway linking injury and disease.NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins.NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia.The role of autophagy in Nmnat-mediated protection against hypoxia-induced dendrite degeneration.Cell Biology of the Mitochondrion.Pretreatment with Human Chorionic Gonadotropin Protects the Neonatal Brain against the Effects of Hypoxic-Ischemic Injury.NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy.Nicotinamide Mononucleotide Adenylyltransferase 1 Protects Neural Cells Against Ischemic Injury in Primary Cultured Neuronal Cells and Mouse Brain with Ischemic Stroke Through AMP-Activated Protein Kinase Activation.Retinal Structure in Cobalamin C Disease: Mechanistic and Therapeutic Implications.Protective effect of P7C3 on retinal ganglion cells from optic nerve injury.
P2860
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P2860
Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Nicotinamide mononucleotide ad ...... citotoxic-necrotic cell death.
@ast
Nicotinamide mononucleotide ad ...... citotoxic-necrotic cell death.
@en
type
label
Nicotinamide mononucleotide ad ...... citotoxic-necrotic cell death.
@ast
Nicotinamide mononucleotide ad ...... citotoxic-necrotic cell death.
@en
prefLabel
Nicotinamide mononucleotide ad ...... citotoxic-necrotic cell death.
@ast
Nicotinamide mononucleotide ad ...... citotoxic-necrotic cell death.
@en
P2093
P2860
P50
P356
P1476
Nicotinamide mononucleotide ad ...... citotoxic-necrotic cell death.
@en
P2093
Christine M Wroge
Donghan Yang
Fatima Sabar
Floy Stewart
Jeffrey J Neil
Mary Beth Finn
Philip B Verghese
P2860
P304
19054-19059
P356
10.1073/PNAS.1107325108
P407
P577
2011-11-04T00:00:00Z