p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
about
The multifaceted roles of the HORMA domain in cellular signalingDNA damage associated with mitosis and cytokinesis failureThe current view for the silencing of the spindle assembly checkpointA role of WT1 in cell division and genomic stabilityOTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic KinasesStructure of the mitotic checkpoint complexThe APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly CheckpointSpatiotemporal regulation of the anaphase-promoting complex in mitosisTranscriptional control of mitosis: deregulation and cancerPhosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic SignalingConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.The spindle assembly checkpoint works like a rheostat rather than a toggle switchDefective sister chromatid cohesion is synthetically lethal with impaired APC/C function.Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint.Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase.Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet).Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing proteinWT1 interacts with MAD2 and regulates mitotic checkpoint functionHow chromosome mis-segregation leads to cancer: lessons from BubR1 mouse modelsCohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrestThe Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis.The biochemistry of mitosisTRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switchingRole of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint complexStructure of an intermediate conformer of the spindle checkpoint protein Mad2p31comet-Induced Cell Death Is Mediated by Binding and Inactivation of Mad2.Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregationPhosphorylation of Xenopus p31(comet) potentiates mitotic checkpoint exit.Making an effective switch at the kinetochore by phosphorylation and dephosphorylation.Regulation of AURORA B function by mitotic checkpoint protein MAD2.Monopolar spindle 1 (MPS1) kinase promotes production of closed MAD2 (C-MAD2) conformer and assembly of the mitotic checkpoint complexThe signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment.Coordinated regulation of p31(Comet) and Mad2 expression is required for cellular proliferationRegulatory mechanisms of kinetochore-microtubule interaction in mitosis.Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore.Panta rhei: the APC/C at steady state.Sharpening the anaphase switch.The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation.Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint.
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P2860
p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
@ast
p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
@en
type
label
p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
@ast
p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
@en
prefLabel
p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
@ast
p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit.
@en
P2860
P50
P356
P1476
p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit
@en
P2093
Anthony Tighe
P2860
P304
P356
10.1242/JCS.093286
P407
P577
2011-11-18T00:00:00Z