Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy.
about
Pathogenesis of the metabolic syndrome: insights from monogenic disordersICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATsEnhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathwayThe relationship between fasting hyperglycemia and insulin secretion in subjects with normal or impaired glucose toleranceChronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.Activated FoxM1 attenuates streptozotocin-mediated β-cell death.Transplanted beta cell response to increased metabolic demand. Changes in beta cell replication and massInvolvement of the autonomic nervous system in the in vivo memory to glucose of pancreatic beta cell in rats.Intra-islet insulin permits glucose to directly suppress pancreatic A cell function.Effects of hemipancreatectomy on pancreatic alpha and beta cell function in healthy human donors.Lipotoxicity and glucotoxicity in type 2 diabetes. Effects on development and progression.The use of animal models in diabetes research.The effect of prednisone on pancreatic islet autografts in dogsGlucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.Insulin therapy for pre-hyperglycemic beta-cell endoplasmic reticulum crowding.Glucotoxicity and beta-cell failure in type 2 diabetes mellitus.In vivo misfolding of proinsulin below the threshold of frank diabetes.Dapagliflozin lowers plasma glucose concentration and improves β-cell functionPreservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations.Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications.Distinct β-cell defects in impaired fasting glucose and impaired glucose toleranceRegulation of pancreatic beta-cell mass.Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β-cell function via glycogen synthase kinase-3β.TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferationTargeting beta-cell mass in type 2 diabetes: promise and limitations of new drugs based on incretinsPDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation.The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality.SGLT2 inhibition: a novel prospective strategy in treatment of diabetes mellitus.Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus.Determinants of glucose toxicity and its reversibility in the pancreatic islet beta-cell line, HIT-T15.TGF-β signalling prevents pancreatic beta cell death after proliferation.Beta-cell rest: a strategy for the prevention of autoimmune diabetes.Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type 2 diabetes.Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus.Mary, Mary, quite contrary, how do your beta-cells fail?beta-cell adaptation in 60% pancreatectomy rats that preserves normoinsulinemia and normoglycemia.Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression.Effect of dietary carbohydrate, fat, and protein on postprandial glycemia and energy intake in cats.Beta-cell function and islet morphology in normal, obese, and obese beta-cell mass-reduced Göttingen minipigs.Muscarinic M1 and M3 receptor binding alterations in pancreas during pancreatic regeneration of young rats.
P2860
Q27024024-5A62E5C3-DA3A-4F9E-8FF4-2867ACB357BCQ28115798-6A7182E2-3A1C-47EF-AAE6-24BB7084D5BFQ28577833-84FE53E2-3B6E-4D76-AD3D-99DDFF234CA1Q33705046-64BF5E09-12E8-4ADE-8260-B6A5C59E3984Q34114554-7C3D7F27-F93B-4231-8308-E4CA3317B14BQ34131699-99C6D0C8-FBE0-4D9C-85FA-D4E4924373C3Q34139310-8FBFF0F8-F7FF-470C-BC0D-E8F809C2525AQ34189030-C85B465C-9C34-43D8-A0A9-4688323F6B30Q34197036-CCC716E1-4FF9-401B-84AD-CF22B8FF4BBBQ34219847-32DF52BB-331F-4445-9AAC-AC5BCD801E49Q34228824-22A92013-077D-44C0-8C03-BB70351A5624Q34255921-4A1BB02A-CECA-4092-A0D7-AFE3A82B40FEQ34356951-B850782D-1C98-48F1-8C8D-93EE01C48466Q34556799-373A183F-7CB0-436A-877E-5029DBE1532EQ34585855-D5F90060-0E33-481D-AF35-67675DE0C9BDQ35065639-976D51BF-E25A-4C61-9383-8C3FB13D4418Q35123549-730C5ED2-250A-431F-89F9-689141E06669Q35578244-543F0E40-F4B5-4067-AC91-B313600146C5Q35604634-8D733F09-9192-4F16-BEEC-ECF29E5DA349Q35651511-A8950C00-A8DB-4064-BDF1-C2E72DC5E034Q35696511-467E5994-0079-4851-B404-5D2D9D1085DCQ36267776-6F420BF5-5718-4694-9E5E-0BEDA9227C59Q36466996-3D36CDFD-C43A-40DA-A9C8-BF416CB0350EQ36720507-547545F9-CB91-4C16-AB0C-8A755592E961Q37091579-15198A99-8327-4135-987D-E536A85B5AC5Q37193305-A3E60467-B064-46F8-A184-9C424D99DE6CQ37424895-FE2C9843-1772-4F8E-9D72-83718459AE86Q38084363-2A8B8918-45B8-43FB-8294-16D12D9EC598Q39805384-8AC958FB-56FC-436E-A987-B693C3D0D90FQ40846007-4ABCDBD1-B8FE-442E-8AC2-F65BF22DC922Q41076082-3873FEFE-4608-4934-96E1-A6B268A5DC5DQ41740281-19B02F07-7F16-491D-AE5C-DA85C489D597Q41756772-B86FA18C-859C-4C91-8E60-CF889A893EFBQ41810412-DD3E4254-8DE2-4E45-BF7E-C4656D57C735Q42131322-6B1343BA-95B2-411E-A0EA-0DA648FFC3D7Q42490543-21B09C13-C444-4E64-9DCC-04AC3A17333DQ43565243-F27BDF21-1A04-452B-9319-BBBD90C88A12Q44883261-1B947C42-6BC3-43E8-BBE5-521E3F7411C3Q45103366-570984AF-B2A0-4955-8C6D-97C2B8FA6F7AQ46908746-FC509FCC-7F11-4038-B64A-C3381686AE86
P2860
Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Minimal chronic hyperglycemia ...... an incomplete pancreatectomy.
@ast
Minimal chronic hyperglycemia ...... an incomplete pancreatectomy.
@en
type
label
Minimal chronic hyperglycemia ...... an incomplete pancreatectomy.
@ast
Minimal chronic hyperglycemia ...... an incomplete pancreatectomy.
@en
prefLabel
Minimal chronic hyperglycemia ...... an incomplete pancreatectomy.
@ast
Minimal chronic hyperglycemia ...... an incomplete pancreatectomy.
@en
P2860
P356
P1476
Minimal chronic hyperglycemia ...... an incomplete pancreatectomy.
@en
P2093
P2860
P304
P356
10.1172/JCI113470
P407
P577
1988-05-01T00:00:00Z