A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
about
Challenges and Opportunities with Non-CYP Enzymes Aldehyde Oxidase, Carboxylesterase, and UDP-Glucuronosyltransferase: Focus on Reaction Phenotyping and Prediction of Human Clearance.Investigational Bruton's tyrosine kinase inhibitors for the treatment of rheumatoid arthritis.Prevalence of Non-Cytochrome P450-Mediated Metabolism in Food and Drug Administration-Approved Oral and Intravenous Drugs: 2006-2015.An overview of aldehyde oxidase: an enzyme of emerging importance in novel drug discovery.Toward an Understanding of Structural Insights of Xanthine and Aldehyde Oxidases: An Overview of their Inhibitors and Role in Various Diseases.Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis.Structure-metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds.Cytochrome P450 and Non-Cytochrome P450 Oxidative Metabolism: Contributions to the Pharmacokinetics, Safety, and Efficacy of Xenobiotics.Going Beyond Common Drug Metabolizing Enzymes: Case Studies of Biotransformation Involving Aldehyde Oxidase, γ-Glutamyl Transpeptidase, Cathepsin B, Flavin-Containing Monooxygenase, and ADP-Ribosyltransferase.In vitro metabolism of alectinib, a novel potent ALK inhibitor, in human: contribution of CYP3A enzymes.
P2860
Q38799423-EAB60A9D-C3E6-4C97-9410-F6C55F40220BQ38826405-D9863563-7E6A-4954-8DFC-8E50D62F7C4BQ38880368-1EB32FED-09AE-43E9-8CC6-0D8AF6CBA8E6Q39016532-9ED6D7C5-4825-40A1-B58E-1C1F288FD9BCQ39411224-5C66234D-DC50-4B43-806B-E4FA83B23586Q39899497-ED77A745-577B-48FB-8A4E-92ADD45A4268Q42290712-EC6A11BA-56B5-4664-B100-0FF677D8B2A4Q46076879-83F7DCAA-37D7-401B-98C5-BE4C8FA61FAAQ46554332-B5FE7F8B-09B9-4EA3-9368-BCBCD5A46931Q53191682-2004F34B-2BE6-4F80-9347-FC11CCAA2E35
P2860
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
@ast
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
@en
type
label
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
@ast
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
@en
prefLabel
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
@ast
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
@en
P2093
P2860
P356
P1476
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834
@en
P2093
Cornelis E C A Hop
Jasleen K Sodhi
Jason S Halladay
Jeffrey P Jones
John T Barr
Lichuan Liu
S Cyrus Khojasteh
Susan Wong
P2860
P304
P356
10.1124/DMD.114.061804
P577
2015-04-06T00:00:00Z