Structure-metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds.

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Toward an Understanding of Structural Insights of Xanthine and Aldehyde Oxidases: An Overview of their Inhibitors and Role in Various Diseases.Direct comparison of the four aldehyde oxidase enzymes present in mouse gives insight into their substrate specificities.

P2860

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P2860

Structure-metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds.

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2017 nî lūn-bûn

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Structure-metabolism relations ...... -aromatic and amide compounds.

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Structure-metabolism relations ...... -aromatic and amide compounds.

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Structure-metabolism relations ...... -aromatic and amide compounds.

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Structure-metabolism relations ...... -aromatic and amide compounds.

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Structure-metabolism relations ...... -aromatic and amide compounds.

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Structure-metabolism relations ...... -aromatic and amide compounds.

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Structure-metabolism relations ...... a-aromatic and amide compounds

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Andrea Cucco

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Andreas Brink

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Martina Ceccarelli

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Nicolò Milani

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P2860

Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase

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Hydrogen bonding interactions of covalently bonded fluorine atoms: from crystallographic data to a new angular function in the GRID force field.

FLAP: GRID molecular interaction fields in virtual screening. validation using the DUD data set.

A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834

Predicting intrinsic clearance for drugs and drug candidates metabolized by aldehyde oxidase.

Absolute quantification of aldehyde oxidase protein in human liver using liquid chromatography-tandem mass spectrometry

Strategies for a comprehensive understanding of metabolism by aldehyde oxidase.

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10.1073/PNAS.1618881114

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English

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Structure-metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds.

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P2860

P2860

Structure-metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds.

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P1433

P1476

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P1476

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P478

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P932