Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
about
Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cellsOpinion: Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetesUsing a baculovirus display library to identify MHC class I mimotopes.Advances in the use of synthetic combinatorial chemistry: mixture-based libraries.Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands.Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells.Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cellsDevelopmental control of CD8 T cell-avidity maturation in autoimmune diabetes.Toxin-coupled MHC class I tetramers can specifically ablate autoreactive CD8+ T cells and delay diabetes in nonobese diabetic mice.Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.In situ recognition of autoantigen as an essential gatekeeper in autoimmune CD8+ T cell inflammationIL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytesThe pathogenicity of self-antigen decreases at high levels of autoantigenicity: a computational approach.Role of the mitochondria in immune-mediated apoptotic death of the human pancreatic β cell line βLox5.RAG-dependent peripheral T cell receptor diversification in CD8+ T lymphocytesMapping I-A(g7) restricted epitopes in murine G6PC2.Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral bloodA pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetesA defect in tryptophan catabolism impairs tolerance in nonobese diabetic miceCTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice.Antidiabetogenic MHC class II promotes the differentiation of MHC-promiscuous autoreactive T cells into FOXP3+ regulatory T cells.Identification of novel IGRP epitopes targeted in type 1 diabetes patients.Rotavirus infection accelerates type 1 diabetes in mice with established insulitisT-cell promiscuity in autoimmune diabetes.Activation of insulin-reactive CD8 T-cells for development of autoimmune diabetes.Microbial antigen mimics activate diabetogenic CD8 T cells in NOD mice.Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes.The potential role of dendritic cells in the therapy of Type 1 diabetes.Adoptive Transfer of mRNA-Transfected T Cells Redirected against Diabetogenic CD8 T Cells Can Prevent Diabetes.Antigen-specific immunotherapies in rheumatic diseases.Enumerating autoreactive T cells in peripheral blood: a big step in diabetes prediction.Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide.Local autoantigen expression as essential gatekeeper of memory T-cell recruitment to islet grafts in diabetic hosts.Crystallization and preliminary X-ray structural studies of a high-affinity CD8alphaalpha co-receptor to pMHCThe proline-rich sequence of CD3epsilon as an amplifier of low-avidity TCR signaling.NOD mice are functionally deficient in the capacity of cross-presentation.Naringenin Modifies the Development of Lineage-Specific Effector CD4 T CellsProgression of autoimmune diabetes driven by avidity maturation of a T-cell population
P2860
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P2860
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
@ast
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
@en
type
label
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
@ast
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
@en
prefLabel
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
@ast
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
@en
P2093
P2860
P356
P1476
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.16.9311
P407
P577
1999-08-01T00:00:00Z