Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734

Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734

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http://www.wikidata.org/entity/Q35605121
Low-level laser therapy regulates microglial function through Src-mediated signaling pathways: implications for neurodegenerative diseasesPyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca2+ entry regulates disassembly of adherens junctions.Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migrationCell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment.Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanismsCDCP1 cleavage is necessary for homodimerization-induced migration of triple-negative breast cancer.New crossroads for potential therapeutic intervention in cancer - intersections between CDCP1, EGFR family members and downstream signaling pathways.Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance.EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface.In vivo cleaved CDCP1 promotes early tumor dissemination via complexing with activated β1 integrin and induction of FAK/PI3K/Akt motility signalingThe tyrosine phosphatase SHP2 associates with CUB domain-containing protein-1 (CDCP1), regulating its expression at the cell surface in a phosphorylation-dependent mannerCD318 is a ligand for CD6.Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration.Prognostic Significance of CDCP1 Expression in Colorectal Cancer and Effect of Its Inhibition on Invasion and Migration.The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer.
P2860

Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734

Item
http://www.wikidata.org/entity/Q35605121
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Cellular settings mediating Sr ...... protein 1 (CDCP1) tyrosine 734
@ast
Cellular settings mediating Sr ...... protein 1 (CDCP1) tyrosine 734
@en
type
label
Cellular settings mediating Sr ...... protein 1 (CDCP1) tyrosine 734
@ast
Cellular settings mediating Sr ...... protein 1 (CDCP1) tyrosine 734
@en
prefLabel
Cellular settings mediating Sr ...... protein 1 (CDCP1) tyrosine 734
@ast
Cellular settings mediating Sr ...... protein 1 (CDCP1) tyrosine 734
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Cellular settings mediating Sr ...... protein 1 (CDCP1) tyrosine 734
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932