Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo.
about
c-Src control of chloride channel support for osteoclast HCl transport and bone resorptionNonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cellsTocotrienols in health and disease: the other half of the natural vitamin E familyc-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: a prerequisite for replication.Paxillin phosphorylation controls invadopodia/podosomes spatiotemporal organization.β1A integrin is a master regulator of invadosome organization and function.The role of cadherin in the generation of multinucleated osteoclasts from mononuclear precursors in murine marrow.Src inhibitors: genomics to therapeutics.Parathyroid hormone-related protein induces spontaneous osteoclast formation via a paracrine cascadeEvidence that the kinase-truncated c-Src regulates NF-κB signaling by targeting NEMO.Substrate recognition by osteoclast precursors induces C-src/microtubule association.The SK-N-AS human neuroblastoma cell line develops osteolytic bone metastases with increased angiogenesis and COX-2 expression.Tocotrienols: the emerging face of natural vitamin ERole of protein-tyrosine phosphatases in regulation of osteoclastic activity.Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate.Interleukin-6 attenuates agonist-mediated calcium mobilization in murine osteoblastic cellsUCS15A, a non-kinase inhibitor of Src signal transduction.The osteoclast: a potential therapeutic target of bone and joint destruction in rheumatoid arthritis.Opposing effects of cyclosporin A and tyrphostin AG-1478 indicate a role for Src protein in the cellular control of mineralization.Protein tyrosine kinase inhibitors increase cytosolic calcium and inhibit actin organization as resorbing activity in rat osteoclasts.
P2860
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P2860
Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Herbimycin A, a pp60c-src tyro ...... tro and hypercalcemia in vivo.
@ast
Herbimycin A, a pp60c-src tyro ...... tro and hypercalcemia in vivo.
@en
type
label
Herbimycin A, a pp60c-src tyro ...... tro and hypercalcemia in vivo.
@ast
Herbimycin A, a pp60c-src tyro ...... tro and hypercalcemia in vivo.
@en
prefLabel
Herbimycin A, a pp60c-src tyro ...... tro and hypercalcemia in vivo.
@ast
Herbimycin A, a pp60c-src tyro ...... tro and hypercalcemia in vivo.
@en
P2093
P2860
P356
P1476
Herbimycin A, a pp60c-src tyro ...... tro and hypercalcemia in vivo.
@en
P2093
G Gutierrez
M Niewolna
P J Williams
P2860
P304
P356
10.1172/JCI116521
P407
P577
1993-06-01T00:00:00Z