Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice.
about
C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptorc-Src control of chloride channel support for osteoclast HCl transport and bone resorptionRegulation of cytochrome c oxidase activity by c-Src in osteoclastsLoss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubismReceptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and functionThe novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formationOsteoimmunology: interactions of the bone and immune systemRegulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolinRegulation of osteoclasts by membrane-derived lipid mediatorsStructure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activityPhosphatidylinositol 3,4,5-trisphosphate directs association of Src homology 2-containing signaling proteins with gelsolinc-Src-dependent transcriptional activation of TFII-IPhysical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitroIdentification of a novel 135-kDa Grb2-binding protein in osteoclastsConformational determinants of phosphotyrosine peptides complexed with the Src SH2 domainDC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cellsTRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingMechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expressionADAM8 enhances osteoclast precursor fusion and osteoclast formation in vitro and in vivoSyk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorptionHuman malignant osteopetrosis: Pathophysiology, management and the role of bone marrow transplantationc-Src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton.3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions3BP2 adapter protein is required for receptor activator of NFκB ligand (RANKL)-induced osteoclast differentiation of RAW264.7 cells.SH3P2 in complex with Cbl and Src.Localization of Tec29 to ring canals is mediated by Src64 and PtdIns(3,4,5)P3-dependent mechanisms.Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival.Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.PSTPIP2 deficiency in mice causes osteopenia and increased differentiation of multipotent myeloid precursors into osteoclasts.Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors.Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts.Osteoclast-stimulating factor interacts with the spinal muscular atrophy gene product to stimulate osteoclast formation.Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.Cadmium osteotoxicity in experimental animals: mechanisms and relationship to human exposures.Commitment and differentiation of stem cells to the osteoclast lineage.Bone is not essential for osteoclast activationMeasurement by vertical scanning profilometry of resorption volume and lacunae depth caused by osteoclasts on dentine slices.Bone resorption caused by three periodontal pathogens in vivo in mice is mediated in part by prostaglandin.Promotion of Tumor Invasion by Tumor-Associated Macrophages: The Role of CSF-1-Activated Phosphatidylinositol 3 Kinase and Src Family Kinase Motility Signaling.
P2860
Q22008788-96D951C4-431C-421E-973C-CEA5C6E5B053Q24296702-AE3D7A89-BEA4-443F-ACB1-9612D5D10925Q24296720-F65A81F5-4A82-4878-A348-D5CCA31E86ABQ24299210-9DA28A8E-AA6D-402C-8D0A-CE289A62BD25Q24537518-F7570D34-BC07-4716-8A85-AD81EB049A35Q24644323-23580AA3-0B78-42F9-B162-9194C96CA466Q24647032-47750A8E-9AFA-4FFE-BA4D-4CDDA164B3A8Q24655113-598B4FCD-CE21-45C6-AD65-6B7D239AFD86Q24671967-01B4D935-DA1C-4170-97A7-D03115CF989CQ26996000-F8718701-B580-4157-9CF6-19E297D309F5Q27626519-19E3D727-E745-49AC-9058-5F9DFA2FED72Q28189293-89BD659F-2861-46F8-B881-C7E476DF92E7Q28213012-439D3ACB-25AD-4F41-BB3A-39ACF599A43FQ28261795-560BAE07-9B62-4DAA-8B8B-64227E406551Q28299116-06E40B75-0E18-4243-90D7-D71F64C40000Q28474536-18CE94C1-7850-447B-90EA-66DBF7BCF764Q28506839-17B00E6C-7F4C-4D91-B9C4-5AEB448B1F7EQ28513445-BFA8AE0E-17CE-4E79-8BDA-9CDD45446C4CQ28584740-5EFF4AA2-8CC4-45EF-994A-98435EEA6EF6Q28587581-32AA5590-7AA1-4CF1-8490-0EC11A6716D3Q28592760-7F501550-72AD-4CE5-84DA-68D85A8C1A8DQ29399804-644789EC-A65A-490E-AF72-2E878185B036Q30010102-2D4B69C7-6E5E-4E90-8152-3935FB2880DAQ30010273-6DAE9F6D-F861-4E52-98A7-3BFA7342672BQ30156881-E0103A1F-6699-40D3-8F9F-DFDDEFF0F586Q30164088-3D6B8E3F-E9BF-4758-B008-76A66FEA6FFCQ30164269-F0BC0B02-2FCC-4323-9B7D-0FFC5E684D0BQ30168513-7717649B-AF39-426D-B51C-0EE478AA6DD6Q30194001-BF030B06-9A4A-4979-A845-BEA452DCDCD2Q30525659-7C1F40E5-6B03-413B-919B-D5C5F0AC67BEQ30579948-8425C02A-5383-4921-AE6D-D1DCE03998AEQ31577127-53EC89C4-02C3-4840-BBFC-4597477C3535Q33292398-8CFE9957-F9CD-4A05-8761-87FC53FF97BCQ33648289-91296831-2446-420B-BC3E-F24F9946B9F3Q33677129-F983E99E-7E85-4D8D-882A-748D21DB07C0Q33678395-9F9D64BC-EC63-44E7-BF02-8A706F490868Q33700392-C8C439A3-BC31-4D39-B874-CAC9F174081FQ33758838-13FBF4F2-BBED-429E-8055-115CCD5284C7Q33761275-DD64B72B-6FE3-4CDB-BB39-BCE25DF3EF23Q33832775-5C702CE5-BA83-48AF-ACAF-FE6909C1D6A5
P2860
Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Requirement of pp60c-src expre ...... rders and resorb bone in mice.
@ast
Requirement of pp60c-src expre ...... rders and resorb bone in mice.
@en
type
label
Requirement of pp60c-src expre ...... rders and resorb bone in mice.
@ast
Requirement of pp60c-src expre ...... rders and resorb bone in mice.
@en
prefLabel
Requirement of pp60c-src expre ...... rders and resorb bone in mice.
@ast
Requirement of pp60c-src expre ...... rders and resorb bone in mice.
@en
P2093
P2860
P356
P1476
Requirement of pp60c-src expre ...... rders and resorb bone in mice.
@en
P2093
P2860
P304
P356
10.1172/JCI116032
P407
P577
1992-10-01T00:00:00Z