Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
about
Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotypeTranscriptional activation of a ras-like gene (kir) by oncogenic tyrosine kinasesCharacterization of four novel ras-like genes expressed in a human teratocarcinoma cell lineIdentification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell linesA human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3KCysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-RasCrystal structure of an active form of RAS protein, a complex of a GTP analog and the HRAS p21 catalytic domainPhospholipase C(epsilon): a novel Ras effectorProtein kinase A-independent activation of ERK and H,K-ATPase by cAMP in native kidney cells: role of Epac IRas oncogenes: split personalitiesAdvantages and limitations of cell-based assays for GTPase activation and regulation.Activation of the mitogen-activated protein kinase pathway in Triton X-100 disrupted NIH-3T3 cells by p21 ras and in vitro by plasma membranes from NIH 3T3 cells.Selection of phage-displayed fab antibodies on the active conformation of ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras.Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras.Chimeric proteins define variable and essential regions of Ha-ras-encoded protein.Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes.The ras-related mouse ypt1 protein can functionally replace the YPT1 gene product in yeast.Genetic analysis of the Kirsten-ras-revertant 1 gene: potentiation of its tumor suppressor activity by specific point mutations.Differential activation of yeast adenylyl cyclase by Ras1 and Ras2 depends on the conserved N terminus.A role for the rap GTPase YlRsr1 in cellular morphogenesis and the involvement of YlRsr1 and the ras GTPase YlRas2 in bud site selection in the dimorphic yeast Yarrowia lipolytica.Molecular model of the G protein alpha subunit based on the crystal structure of the HRAS proteinA ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human plateletsSynthetic peptides of the Rab effector domain inhibit vesicular transport through the secretory pathway.Design of protein struts for self-assembling nanoconstructsFour additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain libraryConsensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens.Functions and functional domains of the GTPase Cdc42pRas signaling pathways mediate NGF-induced enhancement of excitability of small-diameter capsaicin-sensitive sensory neurons from wildtype but not Nf1+/- miceThe GTP-binding protein Rho1p is required for cell cycle progression and polarization of the yeast cell.Purification and characterization of the major nonstructural protein (NS-1) of Aleutian mink disease parvovirusPalmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae.Ras p21 in breast tissue: associations with pathology and cellular localisationA new member of the ras gene superfamily identified in a rat liver cell line.A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments.Residues crucial for Ras interaction with GDP-GTP exchangers.Epac activation sensitizes rat sensory neurons through activation of Ras.The ral gene: a new ras related gene isolated by the use of a synthetic probeSignal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions.
P2860
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P2860
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
@ast
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
@en
type
label
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
@ast
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
@en
prefLabel
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
@ast
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
@en
P2093
P2860
P356
P1476
Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.13.4725
P407
P577
1986-07-01T00:00:00Z