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Aneuploidy in stem cellsDifferent Facets of Copy Number Changes: Permanent, Transient, and AdaptiveEndoreplication and polyploidy: insights into development and diseaseBasic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules.Sensitive and specific detection of mosaic chromosomal abnormalities using the Parent-of-Origin-based Detection (POD) methodElevated tolerance to aneuploidy in cancer cells: estimating the fitness effects of chromosome number alterations by in silico modelling of somatic genome evolutionThe fetal thymus has a unique genomic copy number profile resulting from physiological T cell receptor gene rearrangementChromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors.Whole chromosome gain does not in itself confer cancer-like chromosomal instabilityCompensatory cellular hypertrophy: the other strategy for tissue homeostasis.Mechanisms and consequences of aneuploidy and chromosome instability in the aging brainSingle cell sequencing reveals low levels of aneuploidy across mammalian tissues.Principles of liver regeneration and growth homeostasis.Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease.Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells.Aneuploidy as a mechanism for stress-induced liver adaptation.Hepatocytes polyploidization and cell cycle control in liver physiopathology.Aneuploidy in health, disease, and aging.p53 regulates a mitotic transcription program and determines ploidy in normal mouse liverCancer karyotypes: survival of the fittest2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells.Multinucleation and cell dysfunction induced by amorphous silica nanoparticles in an L-02 human hepatic cell line.Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos.Whole Chromosome Instability induces senescence and promotes SASP.Single cell heterogeneity: why unstable genomes are incompatible with average profiles.New insights into the troubles of aneuploidyTranscriptional effects of gene dose reductionThe Consequences of Chromosome Segregation Errors in Mitosis and Meiosis.Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leapLiver repopulation and regeneration: new approaches to old questions.Chromosomal instability and transcriptome dynamics in cancer.To divide or not to divide: revisiting liver regeneration.Cellular homeostasis and repair in the mammalian liver.Regulation of cytokinesis and its clinical significance.Mosaicism in health and disease - clones picking up speed.MicroRNA-122 regulates polyploidization in the murine liver.Hepatostat: Liver regeneration and normal liver tissue maintenance.Hepatocyte polyploidization and its association with pathophysiological processesFah Knockout Animals as Models for Therapeutic Liver Repopulation.A systematic approach to cancer: evolution beyond selection
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Frequent aneuploidy among normal human hepatocytes.
@ast
Frequent aneuploidy among normal human hepatocytes.
@en
type
label
Frequent aneuploidy among normal human hepatocytes.
@ast
Frequent aneuploidy among normal human hepatocytes.
@en
prefLabel
Frequent aneuploidy among normal human hepatocytes.
@ast
Frequent aneuploidy among normal human hepatocytes.
@en
P2093
P2860
P50
P1433
P1476
Frequent aneuploidy among normal human hepatocytes.
@en
P2093
Amy E Hanlon Newell
Andrew W Duncan
Elizabeth M Wilson
Matthew J Thayer
Susan B Olson
P2860
P356
10.1053/J.GASTRO.2011.10.029
P407
P577
2011-11-02T00:00:00Z