Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
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Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors?Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amidesThe endocannabinoid system in normal and pathological brain ageingBiochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNSChemical probes of endocannabinoid metabolismTherapeutic potential of monoacylglycerol lipase inhibitorsThe pharmacological landscape and therapeutic potential of serine hydrolasesMonoacylglycerol lipase - a target for drug development?Therapeutic potential of inhibitors of endocannabinoid degradation for the treatment of stress-related hyperalgesia in an animal model of chronic painNO2 inhalation promotes Alzheimer's disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medicationSubstrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen ProbesCB2 and GPR55 Receptors as Therapeutic Targets for Systemic Immune DysregulationImpact of Cannabis, Cannabinoids, and Endocannabinoids in the LungsFull Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in MicePhysical activity and the endocannabinoid system: an overviewMultidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticidesCombinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infectionMass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemiaGPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARCMonoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndromeFever Is Mediated by Conversion of Endocannabinoid 2-Arachidonoylglycerol to Prostaglandin E2A Critical Period in Purkinje Cell Development Is Mediated by Local Estradiol Synthesis, Disrupted by Inflammation, and Has Enduring Consequences Only for Males.Activity-based proteomic and metabolomic approaches for understanding metabolismLong-term consequences of perinatal fatty acid amino hydrolase inhibition.Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice.Large-scale neurochemical metabolomics analysis identifies multiple compounds associated with methamphetamine exposureMonoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling.The Anti-Inflammatory Effects of Lipoxygenase and Cyclo-Oxygenase Inhibitors in Inflammation-Induced Human Fetal Glia Cells and the Aβ Degradation Capacity of Human Fetal Astrocytes in an Ex vivo AssayAcute Δ(9)-tetrahydrocannabinol blocks gastric hemorrhages induced by the nonsteroidal anti-inflammatory drug diclofenac sodium in miceMonoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.Endocannabinoid metabolism in neurodegenerative diseasesIdentification of palmitoyl protein thioesterase 1 in human THP1 monocytes and macrophages and characterization of unique biochemical activities for this enzymeMetabolomic strategies to map functions of metabolic pathwaysEndocannabinoids in synaptic plasticity and neuroprotection.Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoidsExploring metabolic pathways and regulation through functional chemoproteomic and metabolomic platformsEndocannabinoid signaling and synaptic function.
P2860
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P2860
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
@ast
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
@en
type
label
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
@ast
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
@en
prefLabel
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
@ast
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
@en
P2093
P2860
P356
P1433
P1476
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.
@en
P2093
Anna M Ward
Aron H Lichtman
Bradley E Morrison
Daniel K Nomura
Jacqueline L Blankman
Jonathan Z Long
Maria Cecilia G Marcondes
Steven G Kinsey
Yun Kyung Hahn
P2860
P304
P356
10.1126/SCIENCE.1209200
P407
P577
2011-10-20T00:00:00Z