Retrotransposition is associated with genome instability during chronological aging.
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Epigenetics and agingPreferential retrotransposition in aging yeast mother cells is correlated with increased genome instability.Growth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocationspiRNA involvement in genome stability and human cancerL1 retrotransposons, cancer stem cells and oncogenesisHuman Genomics. Sleeping dogs of the genomeStem cell aging: mechanisms, regulators and therapeutic opportunities.SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.Extension of Saccharomyces paradoxus chronological lifespan by retrotransposons in certain media conditions is associated with changes in reactive oxygen species.The Ty1 LTR-retrotransposon of budding yeast, Saccharomyces cerevisiaeCombining magnetic sorting of mother cells and fluctuation tests to analyze genome instability during mitotic cell aging in Saccharomyces cerevisiae.Telomerase and retrotransposons: reverse transcriptases that shaped genomesHow The Genome Got a Life Span.Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALSThe three clades of the telomere-associated TLO gene family of Candida albicans have different splicing, localization, and expression features.Extensive somatic L1 retrotransposition in colorectal tumors.Epigenetic regulation of ageing: linking environmental inputs to genomic stability.Ty1 escapes restriction by the self-encoded factor p22 through mutations in capsid.Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila.Chromatin structure and transposable elements in organismal aging.What might retrotransposons teach us about aging?Effect of heavy metals on silencing of engineered long interspersed element-1 retrotransposon in nondividing neuroblastoma cell line.Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues.Useful parasites: the evolutionary biology and biotechnology applications of transposable elements.Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence.The possible roles of human Alu elements in aging.Death by transposition - the enemy within?Dietary and genetic effects on age-related loss of gene silencing reveal epigenetic plasticity of chromatin repression during aging.Hydrogen peroxide induced loss of heterozygosity correlates with replicative lifespan and mitotic asymmetry in Saccharomyces cerevisiaeExtensive chromosomal reshuffling drives evolution of virulence in an asexual pathogen.Piwi Is Required to Limit Exhaustion of Aging Somatic Stem Cells.High reactive oxygen species levels are detected at the end of the chronological life span of translocant yeast cells.The mechanism of ageing: primary role of transposable elements in genome disintegration.Preferential Ty1 retromobility in mother cells and nonquiescent stationary phase cells is associated with increased concentrations of total Gag or processed Gag and is inhibited by exposure to a high concentration of calcium.The Retrotransposon storm and the dangers of a Collyer's genome.Long Non-Coding RNAs in Neuronal Aging.Retrotransposon targeting to RNA polymerase III-transcribed genes.Longevity and transposon defense, the case of termite reproductives.Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE-1 repression
P2860
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P2860
Retrotransposition is associated with genome instability during chronological aging.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Retrotransposition is associated with genome instability during chronological aging.
@ast
Retrotransposition is associated with genome instability during chronological aging.
@en
type
label
Retrotransposition is associated with genome instability during chronological aging.
@ast
Retrotransposition is associated with genome instability during chronological aging.
@en
prefLabel
Retrotransposition is associated with genome instability during chronological aging.
@ast
Retrotransposition is associated with genome instability during chronological aging.
@en
P2860
P356
P1476
Retrotransposition is associated with genome instability during chronological aging.
@en
P2093
Patrick H Maxwell
William C Burhans
P2860
P304
20376-20381
P356
10.1073/PNAS.1100271108
P407
P577
2011-10-20T00:00:00Z