Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression - Wikidata - wikimedia - TriplyDB

Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression

Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression

http://www.wikidata.org/entity/Q35652186

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IRF7: activation, regulation, modification and function Interferon regulatory factor 4 is involved in Epstein-Barr virus-mediated transformation of human B lymphocytes Inflammatory and oxidative stress in rotavirus infection Role of type I interferons in the activation of autoreactive B cells Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7 Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5 p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus.Dual functions of interferon regulatory factors 7C in Epstein-Barr virus-mediated transformation of human B lymphocytes Functional analysis of a dominant negative mutation of interferon regulatory factor 5 TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.Infection in systemic lupus erythematosus: friend or foe?Critical role of IRF-5 in the development of T helper 1 responses to Leishmania donovani infection.IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus Plasmacytoid dendritic cells in HIV infection: striking a delicate balance.TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.Identification of novel methylation markers in hepatocellular carcinoma using a methylation array Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection.Gene expression during the generation and activation of mouse neutrophils: implication of novel functional and regulatory pathways.An integrated genomic and expression analysis of 7q deletion in splenic marginal zone lymphoma IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling RNA-Seq for enrichment and analysis of IRF5 transcript expression in SLE.Requirements for innate immune pathways in environmentally induced autoimmunity.Transcriptional role of p53 in interferon-mediated antiviral immunity.Interferon regulatory factor 4 (IRF-4) targets IRF-5 to regulate Epstein-Barr virus transformation.Two functional variants of IRF5 influence the development of macular edema in patients with non-anterior uveitis IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis A conserved region within interferon regulatory factor 5 controls breast cancer cell migration through a cytoplasmic and transcription-independent mechanism Differential Regulation of the Immune Response in the Spleen and Liver of Mice Infected with Leishmania donovani.Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway.Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus.Aspects of innate immunity in Sjögren's syndrome.Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression.Varicella Viruses Inhibit Interferon-Stimulated JAK-STAT Signaling through Multiple Mechanisms Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.Loss of interferon regulatory factor 5 (IRF5) expression in human ductal carcinoma correlates with disease stage and contributes to metastasis.Genetics of serum concentration of IL-6 and TNFα in systemic lupus erythematosus and rheumatoid arthritis: a candidate gene analysis.Disrupted cooperation between transcription factors across diverse cancer types.

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Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression

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2007年論文

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Role of IFN regulatory factor ...... immunity and tumor suppression

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Role of IFN regulatory factor ...... immunity and tumor suppression

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Role of IFN regulatory factor ...... immunity and tumor suppression

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Role of IFN regulatory factor ...... immunity and tumor suppression

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Role of IFN regulatory factor ...... immunity and tumor suppression

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Akinori Takaoka

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Hideyuki Yanai

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Hui-Min Chen

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Kenya Honda

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Seiji Kondo

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Tadatsugu Taniguchi

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Tak W Mak

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Takayuki Inuzuka

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P2860

PUMA induces the rapid apoptosis of colorectal cancer cells

PUMA, a novel proapoptotic gene, is induced by p53

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

On the role of IRF in host defense

Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death

Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

Interferons, immunity and cancer immunoediting

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