Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.
about
Variable active site loop conformations accommodate the binding of macrocyclic largazole analogues to HDAC8New Modalities for Challenging Targets in Drug Discovery.Novel Methylselenoesters as Antiproliferative Agents.Synthesis and biological evaluation of largazole zinc-binding group analogs.Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes.Largazole Analogues as Histone Deacetylase Inhibitors and Anticancer Agents: An Overview of Structure-Activity Relationships.Novel urushiol derivatives as HDAC8 inhibitors: rational design, virtual screening, molecular docking and molecular dynamics studies.
P2860
Q35243482-EFB46625-9D35-4227-884B-C50329F4EAAAQ38289100-D42A762E-EFD2-48F6-82B6-1CC26224F9C0Q38695892-5C56BE25-B85E-4DC5-A097-154711DEDF76Q38707248-9C1DAB07-9331-477C-B3AD-76A644CA2C43Q38982458-0D7628D2-B620-4129-95D8-F7DE1D52845AQ47631371-521FF9E3-0666-4D50-9964-118F30D284DBQ53208721-AE7CB47C-9C99-4831-889A-F74A61EACFFA
P2860
Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Modular synthesis and biologic ...... acetylase Inhibitor Largazole.
@ast
Modular synthesis and biologic ...... acetylase Inhibitor Largazole.
@en
type
label
Modular synthesis and biologic ...... acetylase Inhibitor Largazole.
@ast
Modular synthesis and biologic ...... acetylase Inhibitor Largazole.
@en
prefLabel
Modular synthesis and biologic ...... acetylase Inhibitor Largazole.
@ast
Modular synthesis and biologic ...... acetylase Inhibitor Largazole.
@en
P2093
P2860
P1476
Modular synthesis and biologic ...... acetylase Inhibitor Largazole.
@en
P2093
Dane J Clausen
James E Bradner
Olaf Wiest
Robert M Williams
William B Smith
P2860
P304
P356
10.1016/J.BMC.2015.03.063
P407
P577
2015-03-31T00:00:00Z