A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
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Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapyPhosphorylation of Puma modulates its apoptotic function by regulating protein stabilityStructural Basis for ASPP2 Recognition by the Tumor Suppressor p73JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stressp73 as a pharmaceutical target for cancer therapySmall-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.Targeting p53 for Novel Anticancer Therapy.iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway.TAp63 induces senescence and suppresses tumorigenesis in vivo.Loss of autophagy causes a synthetic lethal deficiency in DNA repair.Graft-versus-host disease-related cytokine-driven apoptosis depends on p73 in cytokeratin 15-positive target cellsSmall-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.Non-genotoxic anti-neoplastic effects of ellipticine derivative NSC176327 in p53-deficient human colon carcinoma cells involve stimulation of p73Therapeutic prospects for p73 and p63: rising from the shadow of p53.Pharmacological activation of p53 in cancer cellsRecent advances in the molecular diagnosis and prognosis of colorectal cancer.Recombinant adeno-associated virus expressing a p53-derived apoptotic peptide (37AA) inhibits HCC cells growth in vitro and in vivo.p53-family proteins and their regulators: hubs and spokes in tumor suppression.The TP73 complex network: ready for clinical translation in cancer?The prognostic value of the apoptosis pathway in colorectal cancer: a review of the literature on biomarkers identified by immunohistochemistry.E2F1 drives chemotherapeutic drug resistance via ABCG2.p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death.Inhibition of autophagy impairs tumor cell invasion in an organotypic model.DRAM-1 encodes multiple isoforms that regulate autophagy.1,25D3 enhances antitumor activity of gemcitabine and cisplatin in human bladder cancer modelsOncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1.Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax.A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity.Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma.Sertad1 antagonizes iASPP function by hindering its entrance into nuclei to interact with P53 in leukemic cells.The 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction.P53-derived hybrid peptides induce apoptosis of synovial fibroblasts in the rheumatoid joint.Hydration forces as a tool for the optimization of core–shell nanoparticle vectors for cancer gene therapy
P2860
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P2860
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
@ast
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
@en
type
label
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
@ast
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
@en
prefLabel
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
@ast
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.
@en
P2093
P2860
P50
P356
P1476
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo
@en
P2093
Diane Crighton
Helen S Bell
Jim O'Prey
Karen H Vousden
P2860
P304
P356
10.1172/JCI28920
P407
P577
2007-03-08T00:00:00Z